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PE anti-human EOS Antibody

Pricing & Availability
Clone
W16032B (See other available formats)
Regulatory Status
RUO
Other Names
Ikaros family zinc finger protein 4 (IKZF4), ZMFN1A4, KIAA1782
Isotype
Rat IgG2a, κ
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Product Citations
publications
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397403 25 tests 123€
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397404 100 tests 317€
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Description

EOS also known as IKZF4 is an IKAROS Family Member expressed in lymphocytes, specifically in Tregs. It plays an important role in the inhibitory function of Tregs. It may be involved in the development of the central and peripheral nervous systems as well as lymphoid development.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Human EOS recombinant protein (271-520 a.a.)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2832773 (BioLegend Cat. No. 397403)
AB_2832773 (BioLegend Cat. No. 397404)

Antigen Details

Structure
IKAROS family member
Distribution

Lymphocytes, specifically in Tregs

Function
Essential for inhibitory function of Tregs
Interaction
Binds to 5'GGGAATRCC-3' Ikaros-binding sequence
Antigen References
  1. Honma Y, et al. 1999. FEBS Lett. 447:76-80. 
  2. Perdomo J, et al. 2000. J. Biol. Chem. 275:38347-54. 
  3. Westman BJ, et al. 2004. Biochemistry. 43:13318-27. 
  4. Pan F, et al. 2009. Science. 10.1126/science.1176077. 
Gene ID
64375 View all products for this Gene ID
UniProt
View information about EOS on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 0    Revision Date: 01.01.0001

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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