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- Clone
- S22029A (See other available formats)
- Regulatory Status
- RUO
- Other Names
- DEZ, ERV1, RVER1, ChemR23, CML1, GPCR27
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 168602 | 100 µg | 320€ | ||||
CMKLR1 (chemerin chemokine-like receptor1), also know as DEZ or ChemR23, is a ~42 kD G-protein coupled receptor. CMKLR1 is expressed on differentiated adipocytes, dendritic cells, macrophages, and NK cells. It was reported to bind to chemerin which acts as a chemoattractant for dendritic cells and macrophages to inflammatory regions. CMKLR1 is also believed to be involved with adipose tissue homeostasis or adipose tissue metabolism.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse CMKLR1 N-terminal peptide
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_3717215 (BioLegend Cat. No. 168602)
Antigen Details
- Structure
- G-protein coupled receptor, seven-transmembrane domain structure
- Distribution
-
DCs, macrophages, NK cells, neutrophils and adipocytes
- Function
- Chemoattractant for dendritic cells and macrophages to inflammatory regions. Involved with adipose tissue homeostasis and metabolism.
- Interaction
- G proteins
- Ligand/Receptor
- Chemerin, Resolvin E1
- Cell Type
- Dendritic cells, Macrophages
- Biology Area
- Immunology
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
- Methner A, et al. 1997. Biochem Biophys Res Commun. 17:336.
- Parmentier M, et al. 1998. Eur J Immunol. 28:1689.
- Zabel BA, et al. 2006. Exp Hematology. 34:1106.
- Rouger L, et al. 2013. J.Endocrinology. 219:279.
- Gene ID
- 14747 View all products for this Gene ID
- UniProt
- View information about CMKLR1 on UniProt.org
Related FAQs
Other Formats
View All CMKLR1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-mouse CMKLR1 | S22029A | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CMKLR1
C57BL/6 mouse splenocytes were stained with purified anti-mo...
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