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PE/Cyanine7 anti-mouse CD206 (MMR) Antibody PE/Cyanine7 anti-mouse CD206 (MMR) Antibody

Pricing & Availability
Clone
C068C2 (See other available formats)
Regulatory Status
RUO
Other Names
MMR (macrophage mannose receptor), MR (mannose receptor), MRC1
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
C068C2_PECyanine7_CD206_Antibody_1_030724
Thioglycollate-elicited BALB/c mouse peritoneal macrophages were surface stained with CD107b (clone Mac-3) PE, and then intracellularly stained with CD206 (clone C068C2) PE/Cyanine7 (left) or rat IgG2a, κ PE/Cyanine7 isotype control (right).
  • C068C2_PECyanine7_CD206_Antibody_1_030724
    Thioglycollate-elicited BALB/c mouse peritoneal macrophages were surface stained with CD107b (clone Mac-3) PE, and then intracellularly stained with CD206 (clone C068C2) PE/Cyanine7 (left) or rat IgG2a, κ PE/Cyanine7 isotype control (right).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
141719 25 µg DKK945
Check Availability


Need larger quantities of this item?
Request Bulk Quote
141720 100 µg DKK2127
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse CD206 (MMR)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
FC - Verified
Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)4,5.

Application References
  1. Keller J, et al. 2012. Biochem Biophys Res Commun. 417:217. PubMed
  2. Ito H, et al. 2012. J Am Soc Nephrol. 23:1797. PubMed
  3. Yang X, et al. 2015. PNAS. 112:2900. PubMed
  4. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  5. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Fang C, et al. 2022. J Pathol. 256:310. PubMed
  2. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  3. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  4. Yu J, et al. 2022. Nat Commun. 13:7903. PubMed
  5. Tunali G, et al. 2023. J Clin Invest. :. PubMed
  6. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  7. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  8. Schwarz N, et al. 2023. FASEB J. 37:e22846. PubMed
  9. Vanneste D, et al. 2023. Nat Immunol. 24:827. PubMed
  10. Chen Y, et al. 2023. J Nanobiotechnology. 21:98. PubMed
  11. He Q, et al. 2023. Parasit Vectors. 16:139. PubMed
  12. Sagnella SM, et al. 2020. Cancer Cell. 37(3):354-370. PubMed
  13. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  14. Zhang M, et al. 2020. Evid Based Complement Alternat Med. 8591892:2020. PubMed
  15. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  16. Accarias S, et al. 2020. J Cell Sci. 133:. PubMed
  17. Hu J, et al. 2021. Sci Adv. 7:. PubMed
  18. Mason HD, et al. 2021. JCI Insight. 6:e149229. PubMed
  19. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  20. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  21. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  22. Hreha TN, et al. 2020. Front Immunol. 1.597916667. PubMed
  23. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  24. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  25. Nagai Y, et al. 2019. Front Immunol. 10:174. PubMed
  26. Brestoff JR, et al. 2021. Cell Metab. 33:270. PubMed
  27. Wu T, et al. 2021. J Exp Med. :218. PubMed
  28. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  29. Wu Q, et al. 2022. Cell Mol Life Sci. 79:137. PubMed
  30. Ling X, et al. 2021. ACS Nano. 15:765. PubMed
  31. Zheng Y, et al. 2022. Front Pharmacol. 12:816032. PubMed
  32. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  33. Al Mamun A, et al. 2019. Neurochem Int. 127:148. PubMed
  34. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  35. Friedman DJ, et al. 2021. Cancer Immunol Res. 9:952. PubMed
  36. Kennedy EM, et al. 2022. Nat Commun. 13:5907. PubMed
  37. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  38. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  39. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  40. Liu P, et al. 2022. iScience. 25:103867. PubMed
  41. Andriessen EMMA, et al. 2021. EMBO Mol Med. 13:e11754. PubMed
  42. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  43. Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
  44. Pizzurro GA, et al. 2021. Cancers (Basel). 13:. PubMed
  45. Wang G, et al. 2021. Cell Host Microbe. 29(5):777-791.e6. PubMed
  46. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  47. Weinstock NI, et al. 2020. Neuron. 107(1):65-81. PubMed
  48. Lam KC, et al. 2021. Cell. 184:5338. PubMed
  49. Chhatbar C et al. 2018. Cell reports. 25(1):118-129 . PubMed
  50. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  51. Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
  52. Panagi M, et al. 2020. Theranostics. 10:1910. PubMed
  53. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  54. Ravussin A, et al. 2018. Cell Rep. 24:1085. PubMed
  55. Zhang L, et al. 2019. Front Immunol. 1.381944444. PubMed
  56. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  57. Molgora M, et al. 2020. Cell. 182:886. PubMed
  58. Scholz A, et al. 2016. EMBO Mol Med. 8: 39 - 57. PubMed
  59. Silva HM, et al. 2019. J Exp Med. 216:786. PubMed
  60. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  61. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  62. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  63. Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
  64. Zhu Y et al. 2017. The Journal of Neuroscience. 37(9):2362-2376 . PubMed
  65. Güç E, et al. 2020. Methods Enzymol. 91:632. PubMed
  66. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  67. Fang C, et al. 2022. J Pathol. 256:310. PubMed
  68. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  69. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  70. Yu J, et al. 2022. Nat Commun. 13:7903. PubMed
  71. Tunali G, et al. 2023. J Clin Invest. :. PubMed
  72. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  73. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  74. Schwarz N, et al. 2023. FASEB J. 37:e22846. PubMed
  75. Vanneste D, et al. 2023. Nat Immunol. 24:827. PubMed
  76. Chen Y, et al. 2023. J Nanobiotechnology. 21:98. PubMed
  77. He Q, et al. 2023. Parasit Vectors. 16:139. PubMed
  78. Sagnella SM, et al. 2020. Cancer Cell. 37(3):354-370. PubMed
  79. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  80. Zhang M, et al. 2020. Evid Based Complement Alternat Med. 8591892:2020. PubMed
  81. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  82. Accarias S, et al. 2020. J Cell Sci. 133:. PubMed
  83. Hu J, et al. 2021. Sci Adv. 7:. PubMed
  84. Mason HD, et al. 2021. JCI Insight. 6:e149229. PubMed
  85. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  86. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  87. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  88. Hreha TN, et al. 2020. Front Immunol. 1.597916667. PubMed
  89. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  90. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  91. Nagai Y, et al. 2019. Front Immunol. 10:174. PubMed
  92. Brestoff JR, et al. 2021. Cell Metab. 33:270. PubMed
  93. Wu T, et al. 2021. J Exp Med. :218. PubMed
  94. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  95. Wu Q, et al. 2022. Cell Mol Life Sci. 79:137. PubMed
  96. Ling X, et al. 2021. ACS Nano. 15:765. PubMed
  97. Zheng Y, et al. 2022. Front Pharmacol. 12:816032. PubMed
  98. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  99. Al Mamun A, et al. 2019. Neurochem Int. 127:148. PubMed
  100. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  101. Friedman DJ, et al. 2021. Cancer Immunol Res. 9:952. PubMed
  102. Kennedy EM, et al. 2022. Nat Commun. 13:5907. PubMed
  103. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  104. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  105. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  106. Liu P, et al. 2022. iScience. 25:103867. PubMed
  107. Andriessen EMMA, et al. 2021. EMBO Mol Med. 13:e11754. PubMed
  108. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  109. Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
  110. Pizzurro GA, et al. 2021. Cancers (Basel). 13:. PubMed
  111. Wang G, et al. 2021. Cell Host Microbe. 29(5):777-791.e6. PubMed
  112. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  113. Weinstock NI, et al. 2020. Neuron. 107(1):65-81. PubMed
  114. Lam KC, et al. 2021. Cell. 184:5338. PubMed
  115. Chhatbar C et al. 2018. Cell reports. 25(1):118-129 . PubMed
  116. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  117. Huang T, et al. 2022. Nat Commun. 13:3489. PubMed
  118. Panagi M, et al. 2020. Theranostics. 10:1910. PubMed
  119. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  120. Ravussin A, et al. 2018. Cell Rep. 24:1085. PubMed
  121. Zhang L, et al. 2019. Front Immunol. 1.381944444. PubMed
  122. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  123. Molgora M, et al. 2020. Cell. 182:886. PubMed
  124. Scholz A, et al. 2016. EMBO Mol Med. 8: 39 - 57. PubMed
  125. Silva HM, et al. 2019. J Exp Med. 216:786. PubMed
  126. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  127. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  128. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  129. Simoni L, et al. 2020. Cell Rep. 33:108330. PubMed
  130. Zhu Y et al. 2017. The Journal of Neuroscience. 37(9):2362-2376 . PubMed
  131. Güç E, et al. 2020. Methods Enzymol. 91:632. PubMed
  132. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
RRID
AB_2562247 (BioLegend Cat. No. 141719)
AB_2562248 (BioLegend Cat. No. 141720)

Antigen Details

Structure
Type I transmembrane protein, 175 kD, C-type lectin superfamily
Distribution

Macrophages, dendritic cells, Langerhans cells, liver endothelial cells

Function
Pathogen recognition, endocytosis and phagocytosis, antigen presentation
Ligand/Receptor
Antigen containing mannose, fucose, or an N-acetyl glucosamine
Cell Type
Dendritic cells, Endothelial cells, Langerhans cells, Macrophages
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
CD Molecules
Antigen References

1. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501.
2. Apostolopoulos V, et al. 2001. Curr. Mol. Med. 1:469.
3. Burgdorf S, et al. 2006. J. Immunol. 176:6770.
4. McKenzie EJ, et al. 2007. J. Immunol. 178:4975.

Gene ID
17533 View all products for this Gene ID
UniProt
View information about CD206 on UniProt.org

Related FAQs

Why is mouse CD206 stained intracellularly and not via surface staining?

Typically, mouse CD206 surface level is relatively low under normal conditions and so intracellular staining protocol is required to get better signal.

Other Formats

View All CD206 Reagents Request Custom Conjugation
Description Clone Applications
Biotin anti-mouse CD206 (MMR) C068C2 ICFC,FC
Purified anti-mouse CD206 (MMR) C068C2 ICFC,FC
FITC anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE anti-mouse CD206 (MMR) C068C2 ICFC,FC
APC anti-mouse CD206 (MMR) C068C2 ICFC,FC
Alexa Fluor® 488 anti-mouse CD206 (MMR) C068C2 ICFC,FC,IHC-F
Alexa Fluor® 647 anti-mouse CD206 (MMR) C068C2 ICFC,FC,IHC-F
PerCP/Cyanine5.5 anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE/Cyanine7 anti-mouse CD206 (MMR) C068C2 ICFC,FC
Brilliant Violet 421™ anti-mouse CD206 (MMR) C068C2 ICFC,FC,IHC-F,SB
Brilliant Violet 605™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
Brilliant Violet 650™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
Alexa Fluor® 594 anti-mouse CD206 (MMR) C068C2 IHC-F
Brilliant Violet 711™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
Brilliant Violet 785™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE/Dazzle™ 594 anti-mouse CD206 (MMR) C068C2 ICFC,FC
Alexa Fluor® 700 anti-mouse CD206 (MMR) C068C2 ICFC,FC
Spark YG™ 570 anti-mouse CD206 (MMR) C068C2 IHC-F
PE/Cyanine5 anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE/Fire™ 700 anti-mouse CD206 (MMR) C068C2 ICFC,FC
TotalSeq™-B0173 anti-mouse CD206 (MMR) C068C2 ICPG
Spark Red™ 718 anti-mouse CD206 (MMR) (Flexi-Fluor™) C068C2 FC
Spark Blue™ 574 anti-mouse CD206 (MMR) (Flexi-Fluor™) C068C2 FC
TotalSeq™-C0173 anti-mouse CD206 (MMR) Antibody C068C2 ICPG
Spark YG™ 581 anti-mouse CD206 (MMR) (Flexi-Fluor™) C068C2 FC
Spark YG™ 593 anti-mouse CD206 (MMR) (Flexi-Fluor™) Antibody C068C2 FC
Spark NIR™ 685 anti-mouse CD206 (MMR) (Flexi-Fluor™) Antibody C068C2 FC
Go To Top Version: 2    Revision Date: 04/04/2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
C068C2 (See other available formats)
Regulatory Status
RUO
Other Names
MMR (macrophage mannose receptor), MR (mannose receptor), MRC1
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
C068C2_PECyanine7_CD206_Antibody_1_030724
Thioglycollate-elicited BALB/c mouse peritoneal macrophages were surface stained with CD107b (clone Mac-3) PE, and then intracellularly stained with CD206 (clone C068C2) PE/Cyanine7 (left) or rat IgG2a, κ PE/Cyanine7 isotype control (right).
  • C068C2_PECyanine7_CD206_Antibody_1_030724
    Thioglycollate-elicited BALB/c mouse peritoneal macrophages were surface stained with CD107b (clone Mac-3) PE, and then intracellularly stained with CD206 (clone C068C2) PE/Cyanine7 (left) or rat IgG2a, κ PE/Cyanine7 isotype control (right).
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
141719 25 µg DKK945
Check Availability


Need larger quantities of this item?
Request Bulk Quote
141720 100 µg DKK2127
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse CD206 (MMR)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested
FC - Verified
Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone C068C2 recognizes a region similar to clone MR5D3, based on the ability of the clones to block each other. Additional reported applications (for the relevant formats) include: spatial biology (IBEX)4,5.

Application References
  1. Keller J, et al. 2012. Biochem Biophys Res Commun. 417:217. PubMed
  2. Ito H, et al. 2012. J Am Soc Nephrol. 23:1797. PubMed
  3. Yang X, et al. 2015. PNAS. 112:2900. PubMed
  4. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  5. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Fang C, et al. 2022. J Pathol. 256:310. PubMed
  2. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  3. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  4. Yu J, et al. 2022. Nat Commun. 13:7903. PubMed
  5. Tunali G, et al. 2023. J Clin Invest. :. PubMed
  6. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  7. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  8. Schwarz N, et al. 2023. FASEB J. 37:e22846. PubMed
  9. Vanneste D, et al. 2023. Nat Immunol. 24:827. PubMed
  10. Chen Y, et al. 2023. J Nanobiotechnology. 21:98. PubMed
  11. He Q, et al. 2023. Parasit Vectors. 16:139. PubMed
  12. Sagnella SM, et al. 2020. Cancer Cell. 37(3):354-370. PubMed
  13. Rosina M, et al. 2022. Cell Metab. 34:533. PubMed
  14. Zhang M, et al. 2020. Evid Based Complement Alternat Med. 8591892:2020. PubMed
  15. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  16. Accarias S, et al. 2020. J Cell Sci. 133:. PubMed
  17. Hu J, et al. 2021. Sci Adv. 7:. PubMed
  18. Mason HD, et al. 2021. JCI Insight. 6:e149229. PubMed
  19. Zheng W, et al. 2021. Wellcome Open Research. 6:52. PubMed
  20. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  21. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  22. Hreha TN, et al. 2020. Front Immunol. 1.597916667. PubMed
  23. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  24. Glaubitz J, et al. 2022. Nat Commun. 13:4502. PubMed
  25. Nagai Y, et al. 2019. Front Immunol. 10:174. PubMed
  26. Brestoff JR, et al. 2021. Cell Metab. 33:270. PubMed
  27. Wu T, et al. 2021. J Exp Med. :218. PubMed
  28. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  29. Wu Q, et al. 2022. Cell Mol Life Sci. 79:137. PubMed
  30. Ling X, et al. 2021. ACS Nano. 15:765. PubMed
  31. Zheng Y, et al. 2022. Front Pharmacol. 12:816032. PubMed
  32. Goggi JL, et al. 2020. Mol Imaging Biol. 22:1392. PubMed
  33. Al Mamun A, et al. 2019. Neurochem Int. 127:148. PubMed
  34. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  35. Friedman DJ, et al. 2021. Cancer Immunol Res. 9:952. PubMed
  36. Kennedy EM, et al. 2022. Nat Commun. 13:5907. PubMed
  37. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  38. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  39. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  40. Liu P, et al. 2022. iScience. 25:103867. PubMed
  41. Andriessen EMMA, et al. 2021. EMBO Mol Med. 13:e11754. PubMed
  42. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  43. Nowak W, et al. 2020. EBioMedicine. 50:290-305.. PubMed
  44. Pizzurro GA, et al. 2021. Cancers (Basel). 13:. PubMed
  45. Wang G, et al. 2021. Cell Host Microbe. 29(5):777-791.e6. PubMed
  46. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  47. Weinstock NI, et al. 2020. Neuron. 107(1):65-81. PubMed
  48. Lam KC, et al. 2021. Cell. 184:5338. PubMed
  49. Chhatbar C et al. 2018. Cell reports. 25(1):118-129 . PubMed
  50. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
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RRID
AB_2562247 (BioLegend Cat. No. 141719)
AB_2562248 (BioLegend Cat. No. 141720)

Antigen Details

Structure
Type I transmembrane protein, 175 kD, C-type lectin superfamily
Distribution

Macrophages, dendritic cells, Langerhans cells, liver endothelial cells

Function
Pathogen recognition, endocytosis and phagocytosis, antigen presentation
Ligand/Receptor
Antigen containing mannose, fucose, or an N-acetyl glucosamine
Cell Type
Dendritic cells, Endothelial cells, Langerhans cells, Macrophages
Biology Area
Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
CD Molecules
Antigen References

1. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501.
2. Apostolopoulos V, et al. 2001. Curr. Mol. Med. 1:469.
3. Burgdorf S, et al. 2006. J. Immunol. 176:6770.
4. McKenzie EJ, et al. 2007. J. Immunol. 178:4975.

Gene ID
17533 View all products for this Gene ID
UniProt
View information about CD206 on UniProt.org

Related FAQs

Why is mouse CD206 stained intracellularly and not via surface staining?

Typically, mouse CD206 surface level is relatively low under normal conditions and so intracellular staining protocol is required to get better signal.

Other Formats

View All CD206 Reagents Request Custom Conjugation
Description Clone Applications
Biotin anti-mouse CD206 (MMR) C068C2 ICFC,FC
Purified anti-mouse CD206 (MMR) C068C2 ICFC,FC
FITC anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE anti-mouse CD206 (MMR) C068C2 ICFC,FC
APC anti-mouse CD206 (MMR) C068C2 ICFC,FC
Alexa Fluor® 488 anti-mouse CD206 (MMR) C068C2 ICFC,FC,IHC-F
Alexa Fluor® 647 anti-mouse CD206 (MMR) C068C2 ICFC,FC,IHC-F
PerCP/Cyanine5.5 anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE/Cyanine7 anti-mouse CD206 (MMR) C068C2 ICFC,FC
Brilliant Violet 421™ anti-mouse CD206 (MMR) C068C2 ICFC,FC,IHC-F,SB
Brilliant Violet 605™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
Brilliant Violet 650™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
Alexa Fluor® 594 anti-mouse CD206 (MMR) C068C2 IHC-F
Brilliant Violet 711™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
Brilliant Violet 785™ anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE/Dazzle™ 594 anti-mouse CD206 (MMR) C068C2 ICFC,FC
Alexa Fluor® 700 anti-mouse CD206 (MMR) C068C2 ICFC,FC
Spark YG™ 570 anti-mouse CD206 (MMR) C068C2 IHC-F
PE/Cyanine5 anti-mouse CD206 (MMR) C068C2 ICFC,FC
PE/Fire™ 700 anti-mouse CD206 (MMR) C068C2 ICFC,FC
TotalSeq™-B0173 anti-mouse CD206 (MMR) C068C2 ICPG
Spark Red™ 718 anti-mouse CD206 (MMR) (Flexi-Fluor™) C068C2 FC
Spark Blue™ 574 anti-mouse CD206 (MMR) (Flexi-Fluor™) C068C2 FC
TotalSeq™-C0173 anti-mouse CD206 (MMR) Antibody C068C2 ICPG
Spark YG™ 581 anti-mouse CD206 (MMR) (Flexi-Fluor™) C068C2 FC
Spark YG™ 593 anti-mouse CD206 (MMR) (Flexi-Fluor™) Antibody C068C2 FC
Spark NIR™ 685 anti-mouse CD206 (MMR) (Flexi-Fluor™) Antibody C068C2 FC
Go To Top Version: 2    Revision Date: 04/04/2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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