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PE/Cyanine7 anti-mouse TCR β chain Antibody PE/Cyanine7 anti-mouse TCR β chain Antibody

Pricing & Availability
Clone
H57-597 (See other available formats)
Regulatory Status
RUO
Other Names
TCR-β chain, TCR-β, β-TCR
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
H57-597_PECy7_122607
C57BL/6 mouse splenocytes stained with H57-597 PE/Cyanine7
  • H57-597_PECy7_122607
    C57BL/6 mouse splenocytes stained with H57-597 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
109221 25 µg DKK559
Check Availability


Need larger quantities of this item?
Request Bulk Quote
109222 100 µg DKK1307
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Request Bulk Quote
Description

T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Affinity purified TCR from mouse DO-11.10 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

H57-597 is a hamster mAb directed to an epitope of the C region of TCR ß chain12. The H57-597 antibody does not cross-react with ?/d TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate a/ß TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation2, in vitro stimulation2,3, in vivo depletion4-6, and immunohistochemical staining of acetone-fixed frozen sections7,8,9. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 109253-109258).

Application References
  1. Gascoigne NJ. 1990. J. Biol. Chem. 265:9296.
  2. Kruisbeek A, et al. 1991. In Current Protocols in Immunology. pp. 3.12.1. (Costim IP)
  3. Davenport C, et al. 1995. J. Immunol. 155:3742. (Costim)
  4. Drobyski W, et al. 1996. Blood 87:5355. (Deplete)
  5. Kummer U, et al. 2001. Immunol. Lett. 75:153. (Deplete)
  6. van der Heyde HC, et al. 1995. J. Immunol. 154:3985. (Deplete)
  7. Tomita K, et al. 1999. Genes Dev. 13:1203. (IHC)
  8. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)
  9. Ponomarev ED, et al. 2007. J. Immunol. 178:39. (IHC)
  10. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed
  11. Tsukumo S, et al. 2006. J.Immunol. 177:8365. (FC) PubMed
  12. Grégoire C, et al. 1991. Proc. Natl. Acad. Sci USA 88:8077.
Product Citations
  1. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  2. Man SM et al. 2016. Cell. 167(2):382-396 . PubMed
  3. Vono M, et al. 2020. Cell Reports. 28(7):1773-1784.e5.. PubMed
  4. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  5. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  6. Kulkarni R, et al. 2023. Life Sci Alliance. 6: . PubMed
  7. Yeh CH, et al. 2022. Immunity. 55:272. PubMed
  8. Friedman D, et al. 2022. J Immunol. 208:1845. PubMed
  9. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  10. Pi C, et al. 2022. Cancers (Basel). 14:. PubMed
  11. Martens R, et al. 2020. Nat Commun. 11:1114. PubMed
  12. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  13. Failer T, et al. 2022. J Clin Invest. . PubMed
  14. Moodley D, et al. 2016. Proc Natl Acad Sci U S A. 113: 9852 - 9857. PubMed
  15. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  16. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  17. Nieuwenhuijze A, et al. 2014. Am J Pathol. 184:184. PubMed
  18. Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
  19. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  20. Sugimoto C, et al. 2022. Elife. 11:. PubMed
  21. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  22. Gordon RA, et al. 2020. PLoS One. 15:e0226396. PubMed
  23. Krementsov DN, et al. 2018. Front Immunol. 9:1622. PubMed
  24. Sandrock I, et al. 2015. PLoS One. 10: 0145010. PubMed
  25. Kinsella S, et al. 2021. Cell Rep. 37:109789. PubMed
  26. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  27. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  28. Ribeiro-Gomes F, et al. 2015. Cell Death Dis. 6: 2018. PubMed
  29. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  30. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  31. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  32. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  33. Sun H, et al. 2022. Front Immunol. 13:818017. PubMed
  34. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  35. Kyburz A, et al. 2017. Clin Exp Allergy. 47:1331. PubMed
  36. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  37. Fu S, et al. 2020. Nat Commun. 0.7625. PubMed
  38. Sadik A, et al. 2020. Cell. 1252:182. PubMed
  39. Zhang Q, et al. 2021. Front Cell Dev Biol. 9:655552. PubMed
  40. Sencio V, et al. 2020. Cell Reports. 30(9):2934-2947. PubMed
  41. Udden SN et al. 2019. eLife. 8 pii: e40396. PubMed
  42. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  43. Matas-Rico E, et al. 2021. Cell Rep. 37:110013. PubMed
  44. Dong X, et al. 2022. Front Immunol. 13:896472. PubMed
  45. Li J, et al. 2020. Development. :. PubMed
  46. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  47. Thornton T, et al. 2016. Nat Commun. 7:10553. PubMed
  48. Zhang Q, et al. 2022. Commun Biol. 5:544. PubMed
  49. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
  50. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  51. Baars MJD, et al. 2020. Eur J Immunol. . PubMed
  52. Wang X, et al. 2021. Cell. 184:5357. PubMed
  53. Sell S, et al. 2015. PLoS Pathog. 11:1004481. PubMed
  54. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  55. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  56. Liang Z, et al. 2017. Autophagy. 14:505. PubMed
  57. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  58. Wang X, et al. 2022. Elife. 11:. PubMed
  59. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  60. Hall JA, et al. 2020. Cell Metabolism. 32(4):665-675.e6. PubMed
  61. Nabekura T, et al. 2020. Immunity. 96:52. PubMed
  62. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  63. Liang Z, et al. 2022. iScience. 25:105233. PubMed
  64. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  65. Man SM et al. 2016. Cell. 167(2):382-396 . PubMed
  66. Vono M, et al. 2020. Cell Reports. 28(7):1773-1784.e5.. PubMed
  67. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  68. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  69. Kulkarni R, et al. 2023. Life Sci Alliance. 6: . PubMed
  70. Yeh CH, et al. 2022. Immunity. 55:272. PubMed
  71. Friedman D, et al. 2022. J Immunol. 208:1845. PubMed
  72. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  73. Pi C, et al. 2022. Cancers (Basel). 14:. PubMed
  74. Martens R, et al. 2020. Nat Commun. 11:1114. PubMed
  75. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  76. Failer T, et al. 2022. J Clin Invest. . PubMed
  77. Moodley D, et al. 2016. Proc Natl Acad Sci U S A. 113: 9852 - 9857. PubMed
  78. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  79. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  80. Nieuwenhuijze A, et al. 2014. Am J Pathol. 184:184. PubMed
  81. Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
  82. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  83. Sugimoto C, et al. 2022. Elife. 11:. PubMed
  84. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  85. Gordon RA, et al. 2020. PLoS One. 15:e0226396. PubMed
  86. Krementsov DN, et al. 2018. Front Immunol. 9:1622. PubMed
  87. Sandrock I, et al. 2015. PLoS One. 10: 0145010. PubMed
  88. Kinsella S, et al. 2021. Cell Rep. 37:109789. PubMed
  89. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  90. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  91. Ribeiro-Gomes F, et al. 2015. Cell Death Dis. 6: 2018. PubMed
  92. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  93. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  94. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  95. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  96. Sun H, et al. 2022. Front Immunol. 13:818017. PubMed
  97. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  98. Kyburz A, et al. 2017. Clin Exp Allergy. 47:1331. PubMed
  99. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  100. Fu S, et al. 2020. Nat Commun. 0.7625. PubMed
  101. Sadik A, et al. 2020. Cell. 1252:182. PubMed
  102. Zhang Q, et al. 2021. Front Cell Dev Biol. 9:655552. PubMed
  103. Sencio V, et al. 2020. Cell Reports. 30(9):2934-2947. PubMed
  104. Udden SN et al. 2019. eLife. 8 pii: e40396. PubMed
  105. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  106. Matas-Rico E, et al. 2021. Cell Rep. 37:110013. PubMed
  107. Dong X, et al. 2022. Front Immunol. 13:896472. PubMed
  108. Li J, et al. 2020. Development. :. PubMed
  109. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  110. Thornton T, et al. 2016. Nat Commun. 7:10553. PubMed
  111. Zhang Q, et al. 2022. Commun Biol. 5:544. PubMed
  112. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
  113. Muri J, et al. 2020. Cell Reports. 29(9):2731-2744.e4.. PubMed
  114. Baars MJD, et al. 2020. Eur J Immunol. . PubMed
  115. Wang X, et al. 2021. Cell. 184:5357. PubMed
  116. Sell S, et al. 2015. PLoS Pathog. 11:1004481. PubMed
  117. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  118. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  119. Liang Z, et al. 2017. Autophagy. 14:505. PubMed
  120. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  121. Wang X, et al. 2022. Elife. 11:. PubMed
  122. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  123. Hall JA, et al. 2020. Cell Metabolism. 32(4):665-675.e6. PubMed
  124. Nabekura T, et al. 2020. Immunity. 96:52. PubMed
  125. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  126. Liang Z, et al. 2022. iScience. 25:105233. PubMed
RRID
AB_893627 (BioLegend Cat. No. 109221)
AB_893625 (BioLegend Cat. No. 109222)

Antigen Details

Structure
Ig superfamily, CD3/TCR complex with CD3 and TCR α subunit
Distribution

Majority of T cells and thymocytes (correlated to differentiation)

Function
Antigen recognition, T cell activation
Ligand/Receptor
Peptide bound-MHC class I and II
Antigen References

1. Davis MM, et al. 1998. Ann. Rev. Immunol. 16:523.
2. Huppa JB, et al. 2003. Nat. Immunol. 4:749.
3. Kubo R, et al. 1989. J. Immunol. 142:2736.

Gene ID
21577 View all products for this Gene ID
UniProt
View information about TCR beta chain on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All TCR β chain Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse TCR β chain H57-597 FC
Biotin anti-mouse TCR β chain H57-597 FC,IHC-F
FITC anti-mouse TCR β chain H57-597 FC,IHC-F
PE anti-mouse TCR β chain H57-597 FC
PE/Cyanine5 anti-mouse TCR β chain H57-597 FC
Purified anti-mouse TCR β chain H57-597 FC,CyTOF®,IHC-F,IP,Costim,Depletion
Alexa Fluor® 488 anti-mouse TCR β chain H57-597 FC,IHC-F
Alexa Fluor® 647 anti-mouse TCR β chain H57-597 FC,IHC-F
APC/Cyanine7 anti-mouse TCR β chain H57-597 FC
PE/Cyanine7 anti-mouse TCR β chain H57-597 FC
Alexa Fluor® 700 anti-mouse TCR β chain H57-597 FC
Pacific Blue™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 421™ anti-mouse TCR β chain H57-597 FC,IHC-F
PerCP/Cyanine5.5 anti-mouse TCR β chain H57-597 FC
Brilliant Violet 570™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 510™ anti-mouse TCR β chain H57-597 FC,IHC-F
Purified anti-mouse TCR β chain (Maxpar® Ready) H57-597 FC,CyTOF®
Alexa Fluor® 594 anti-mouse TCR β chain H57-597 FC,IHC-F
PE/Dazzle™ 594 anti-mouse TCR β chain H57-597 FC
Brilliant Violet 605™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 711™ anti-mouse TCR β chain H57-597 FC
APC/Fire™ 750 anti-mouse TCR β chain H57-597 FC
TotalSeq™-A0120 anti-mouse TCR β chain H57-597 PG
Brilliant Violet 785™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 650™ anti-mouse TCR β chain H57-597 FC
Ultra-LEAF™ Purified anti-mouse TCR β chain H57-597 FC,CyTOF®,IHC-F,IP,Costim,Depletion
TotalSeq™-C0120 anti-mouse TCR β chain H57-597 PG
TotalSeq™-B0120 anti-mouse TCR β chain H57-597 PG
Spark Red™ 718 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark PLUS UV395™ anti-mouse TCR β chain H57-597 FC
TotalSeq™-D0120 anti-mouse TCR β chain H57-597 PG
Spark Blue™ 574 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark Blue™ 550 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark YG™ 581 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark YG™ 593 anti-mouse TCR β chain (Flexi-Fluor™) Antibody H57-597 FC
Spark NIR™ 685 anti-mouse TCR β chain (Flexi-Fluor™) Antibody H57-597 FC
Spark UV™ 387 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Go To Top Version: 2    Revision Date: 02/06/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
H57-597 (See other available formats)
Regulatory Status
RUO
Other Names
TCR-β chain, TCR-β, β-TCR
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
H57-597_PECy7_122607
C57BL/6 mouse splenocytes stained with H57-597 PE/Cyanine7
  • H57-597_PECy7_122607
    C57BL/6 mouse splenocytes stained with H57-597 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
109221 25 µg DKK559
Check Availability


Need larger quantities of this item?
Request Bulk Quote
109222 100 µg DKK1307
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Affinity purified TCR from mouse DO-11.10 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

H57-597 is a hamster mAb directed to an epitope of the C region of TCR ß chain12. The H57-597 antibody does not cross-react with ?/d TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate a/ß TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation2, in vitro stimulation2,3, in vivo depletion4-6, and immunohistochemical staining of acetone-fixed frozen sections7,8,9. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 109253-109258).

Application References
  1. Gascoigne NJ. 1990. J. Biol. Chem. 265:9296.
  2. Kruisbeek A, et al. 1991. In Current Protocols in Immunology. pp. 3.12.1. (Costim IP)
  3. Davenport C, et al. 1995. J. Immunol. 155:3742. (Costim)
  4. Drobyski W, et al. 1996. Blood 87:5355. (Deplete)
  5. Kummer U, et al. 2001. Immunol. Lett. 75:153. (Deplete)
  6. van der Heyde HC, et al. 1995. J. Immunol. 154:3985. (Deplete)
  7. Tomita K, et al. 1999. Genes Dev. 13:1203. (IHC)
  8. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)
  9. Ponomarev ED, et al. 2007. J. Immunol. 178:39. (IHC)
  10. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed
  11. Tsukumo S, et al. 2006. J.Immunol. 177:8365. (FC) PubMed
  12. Grégoire C, et al. 1991. Proc. Natl. Acad. Sci USA 88:8077.
Product Citations
  1. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  2. Man SM et al. 2016. Cell. 167(2):382-396 . PubMed
  3. Vono M, et al. 2020. Cell Reports. 28(7):1773-1784.e5.. PubMed
  4. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  5. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  6. Kulkarni R, et al. 2023. Life Sci Alliance. 6: . PubMed
  7. Yeh CH, et al. 2022. Immunity. 55:272. PubMed
  8. Friedman D, et al. 2022. J Immunol. 208:1845. PubMed
  9. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  10. Pi C, et al. 2022. Cancers (Basel). 14:. PubMed
  11. Martens R, et al. 2020. Nat Commun. 11:1114. PubMed
  12. Wiesner DL, et al. 2020. Cell Host Microbe. 614:27. PubMed
  13. Failer T, et al. 2022. J Clin Invest. . PubMed
  14. Moodley D, et al. 2016. Proc Natl Acad Sci U S A. 113: 9852 - 9857. PubMed
  15. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  16. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  17. Nieuwenhuijze A, et al. 2014. Am J Pathol. 184:184. PubMed
  18. Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
  19. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  20. Sugimoto C, et al. 2022. Elife. 11:. PubMed
  21. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  22. Gordon RA, et al. 2020. PLoS One. 15:e0226396. PubMed
  23. Krementsov DN, et al. 2018. Front Immunol. 9:1622. PubMed
  24. Sandrock I, et al. 2015. PLoS One. 10: 0145010. PubMed
  25. Kinsella S, et al. 2021. Cell Rep. 37:109789. PubMed
  26. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  27. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  28. Ribeiro-Gomes F, et al. 2015. Cell Death Dis. 6: 2018. PubMed
  29. Park D, et al. 2020. Cancer Res. 80:4172. PubMed
  30. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  31. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  32. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  33. Sun H, et al. 2022. Front Immunol. 13:818017. PubMed
  34. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  35. Kyburz A, et al. 2017. Clin Exp Allergy. 47:1331. PubMed
  36. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  37. Fu S, et al. 2020. Nat Commun. 0.7625. PubMed
  38. Sadik A, et al. 2020. Cell. 1252:182. PubMed
  39. Zhang Q, et al. 2021. Front Cell Dev Biol. 9:655552. PubMed
  40. Sencio V, et al. 2020. Cell Reports. 30(9):2934-2947. PubMed
  41. Udden SN et al. 2019. eLife. 8 pii: e40396. PubMed
  42. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  43. Matas-Rico E, et al. 2021. Cell Rep. 37:110013. PubMed
  44. Dong X, et al. 2022. Front Immunol. 13:896472. PubMed
  45. Li J, et al. 2020. Development. :. PubMed
  46. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  47. Thornton T, et al. 2016. Nat Commun. 7:10553. PubMed
  48. Zhang Q, et al. 2022. Commun Biol. 5:544. PubMed
  49. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
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RRID
AB_893627 (BioLegend Cat. No. 109221)
AB_893625 (BioLegend Cat. No. 109222)

Antigen Details

Structure
Ig superfamily, CD3/TCR complex with CD3 and TCR α subunit
Distribution

Majority of T cells and thymocytes (correlated to differentiation)

Function
Antigen recognition, T cell activation
Ligand/Receptor
Peptide bound-MHC class I and II
Antigen References

1. Davis MM, et al. 1998. Ann. Rev. Immunol. 16:523.
2. Huppa JB, et al. 2003. Nat. Immunol. 4:749.
3. Kubo R, et al. 1989. J. Immunol. 142:2736.

Gene ID
21577 View all products for this Gene ID
UniProt
View information about TCR beta chain on UniProt.org

Other Formats

View All TCR β chain Reagents Request Custom Conjugation
Description Clone Applications
APC anti-mouse TCR β chain H57-597 FC
Biotin anti-mouse TCR β chain H57-597 FC,IHC-F
FITC anti-mouse TCR β chain H57-597 FC,IHC-F
PE anti-mouse TCR β chain H57-597 FC
PE/Cyanine5 anti-mouse TCR β chain H57-597 FC
Purified anti-mouse TCR β chain H57-597 FC,CyTOF®,IHC-F,IP,Costim,Depletion
Alexa Fluor® 488 anti-mouse TCR β chain H57-597 FC,IHC-F
Alexa Fluor® 647 anti-mouse TCR β chain H57-597 FC,IHC-F
APC/Cyanine7 anti-mouse TCR β chain H57-597 FC
PE/Cyanine7 anti-mouse TCR β chain H57-597 FC
Alexa Fluor® 700 anti-mouse TCR β chain H57-597 FC
Pacific Blue™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 421™ anti-mouse TCR β chain H57-597 FC,IHC-F
PerCP/Cyanine5.5 anti-mouse TCR β chain H57-597 FC
Brilliant Violet 570™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 510™ anti-mouse TCR β chain H57-597 FC,IHC-F
Purified anti-mouse TCR β chain (Maxpar® Ready) H57-597 FC,CyTOF®
Alexa Fluor® 594 anti-mouse TCR β chain H57-597 FC,IHC-F
PE/Dazzle™ 594 anti-mouse TCR β chain H57-597 FC
Brilliant Violet 605™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 711™ anti-mouse TCR β chain H57-597 FC
APC/Fire™ 750 anti-mouse TCR β chain H57-597 FC
TotalSeq™-A0120 anti-mouse TCR β chain H57-597 PG
Brilliant Violet 785™ anti-mouse TCR β chain H57-597 FC
Brilliant Violet 650™ anti-mouse TCR β chain H57-597 FC
Ultra-LEAF™ Purified anti-mouse TCR β chain H57-597 FC,CyTOF®,IHC-F,IP,Costim,Depletion
TotalSeq™-C0120 anti-mouse TCR β chain H57-597 PG
TotalSeq™-B0120 anti-mouse TCR β chain H57-597 PG
Spark Red™ 718 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark PLUS UV395™ anti-mouse TCR β chain H57-597 FC
TotalSeq™-D0120 anti-mouse TCR β chain H57-597 PG
Spark Blue™ 574 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark Blue™ 550 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark YG™ 581 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Spark YG™ 593 anti-mouse TCR β chain (Flexi-Fluor™) Antibody H57-597 FC
Spark NIR™ 685 anti-mouse TCR β chain (Flexi-Fluor™) Antibody H57-597 FC
Spark UV™ 387 anti-mouse TCR β chain (Flexi-Fluor™) H57-597 FC
Go To Top Version: 2    Revision Date: 02/06/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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