Purified anti-β-Amyloid, x-42 (Previously Covance catalog# SIG-39168)

Pricing & Availability
Clone
BA3-9 (See other available formats)
Regulatory Status
RUO
Other Names
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, SIG-39168-050, APP
Previously
Covance Catalog# SIG-39168
Isotype
Rabbit IgG
Ave. Rating
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Product Citations
publications
Cat # Size Price Quantity Check Availability Save
825301 50 µg 180€
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Description

Soluble Aβ (Amyloid-beta, beta-amyloid, or Abeta) peptides, 36 to 43 amino acids in length, are natural proteolytic cleavage products of amyloid precursor protein (APP). However, soluble abnormally aggregated Aβ species are associated with Alzheimer's disease (AD), can be toxic to neurons, and insoluble Aβ aggregates are the main component of cerebral amyloid plaques, which are a pathological hallmark of AD.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Rabbit
Formulation
Phosphate-buffered solution (no preservatives or carrier proteins).
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

ELISA - Quality tested
IHC-F - Verified
ICC - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay.

Application Notes

This antibody is effective in ELISA, immunocytochemistry (ICC), and has been verified for immunohistochemistry on frozen human tissue.

Clone BA3-9 is reactive to the c-terminus of ß-amyloid and specific for the isoform that ends at the 42nd amino acid.

Application References
  1. Ghate PS, et al. 2010. Springerplus. 3:161. (ICC) PubMed
  2. Ingham V, et al. 2014. J. Neuroinflammation. 11:115. (ELISA)
RRID
AB_2564889 (BioLegend Cat. No. 825301)

Antigen Details

Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
APP/β-Amyloid
Gene ID
351 View all products for this Gene ID
UniProt
View information about beta-Amyloid on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 5    Revision Date: 12/13/2016

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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  • Purified anti-β-Amyloid, x-42

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