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- Clone
- A21111E (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Dipeptidyl peptidase-4, adenosine deaminase complexing protein 2, ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5, DPP4
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with purified CD26 (clone A21111E) (left) or purified mouse IgG2b, κ isotype control (right) followed by anti-mouse IgG PE. Cells were washed and then stained with anti-human CD3 (clone OKT3) APC.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 315505 | 100 µg | 76€ | ||||
CD26, also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV), is a 110 kD type II membrane protein. It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human DPP4 (AA 41-766)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Antigen Details
- Structure
- Peptidases and ectoenzyme families, type II glycoprotein, 110 kD
- Distribution
-
Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages
- Function
- Dipeptidyl peptidase, T cell costimulation, HIV entry
- Ligand/Receptor
- Adenosine-deaminase, collagen
- Cell Type
- B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
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- Kameoka J, et al. 1993. Science. 261:466-9.
- Dang N, et al. 1990. J. Exp. Med. 172:649-52.
- Gene ID
- 1803 View all products for this Gene ID
- UniProt
- View information about CD26 on UniProt.org
Related FAQs
Other Formats
View All CD26 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD26 | A21111E | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD26
Human peripheral blood lymphocytes were stained with purifie...
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