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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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101301 50 µg 29€
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101302 500 µg 92€
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Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  2. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  3. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  4. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  5. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  6. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  7. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  8. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  9. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  10. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  11. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  12. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  13. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  14. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  15. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  16. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  17. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  18. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  19. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  20. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  21. Miyao T, et al. 2022. Elife. 11: . PubMed
  22. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  23. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  24. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  25. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  26. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  27. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  28. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  29. Akalu YT, et al. 2022. Elife. 11: . PubMed
  30. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  31. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  32. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  33. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  34. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  35. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  36. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  37. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  38. Cousin N, et al. 2022. Cells. 12: . PubMed
  39. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  40. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  41. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  42. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  43. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  44. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  45. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  46. Liu X, et al. 2022. Pain. 163:508. PubMed
  47. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  48. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  49. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  50. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  51. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  52. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  53. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  54. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  55. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  56. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  57. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  58. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  59. Barkaway A, et al. 2021. Immunity. . PubMed
  60. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  61. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  62. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  63. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  64. Ding P, et al. 2022. Elife. 11:. PubMed
  65. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  66. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  67. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  68. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  69. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  70. Li L, et al. 2023. iScience. 26:106095. PubMed
  71. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  72. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  73. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  74. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  75. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  76. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  77. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  78. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  79. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  80. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  81. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  82. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  83. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  84. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  85. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  86. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  87. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  88. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  89. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  90. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  91. Uranga, R. M., Nishii, A., et al. 2025. Mol Metab. 100(0),102226. PubMed
  92. Wei, S., Shou, D., et al. 2025. Adv Sci (Weinh). 12(46),e09351. PubMed
  93. Han, X., Bai, X., et al. 2025. Oncoimmunology. 14(1),2581910. PubMed
  94. Reich, M., Franz, T., et al. 2025. iScience. 28(12),113929. PubMed
  95. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  96. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  97. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  98. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  99. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  100. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  101. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  102. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  103. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  104. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  105. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  106. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  107. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  108. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  109. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  110. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  111. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  112. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  113. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  114. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  115. Mevel R, et al. 2020. eLife. 9:00. PubMed
  116. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  117. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  118. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  119. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  120. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  121. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  122. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  123. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  124. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  125. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  126. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  127. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  128. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  129. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  130. Feng J, et al. 2021. iScience. 24:103004. PubMed
  131. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  132. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  133. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  134. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  135. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  136. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  137. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  138. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  139. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  140. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  141. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  142. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  143. Goel S, et al. 2017. Nature. 548:471. PubMed
  144. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  145. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  146. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  147. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  148. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  149. Diao L, et al. 2022. iScience. 25:105511. PubMed
  150. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  151. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  152. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  153. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  154. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  155. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  156. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  157. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  158. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  159. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  160. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  161. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  162. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  163. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  164. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  165. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  166. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  167. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  168. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  169. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  170. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  171. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  172. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  173. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  174. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  175. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  176. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  177. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  178. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  179. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  180. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  181. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  182. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  183. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  184. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  185. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  186. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  187. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  188. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  189. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  190. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  191. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  192. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  193. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  194. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  195. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  196. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  197. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  198. Tal MC, et al. 2020. MBio. 11:00. PubMed
  199. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  200. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  201. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  202. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  203. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  204. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  205. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  206. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  207. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  208. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  209. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  210. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  211. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  212. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  213. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  214. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  215. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  216. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  217. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  218. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  219. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  220. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  221. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  222. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  223. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  224. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  225. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  226. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  227. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  228. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  229. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  230. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  231. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  232. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  233. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  234. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  235. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  236. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  237. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  238. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  239. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  240. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  241. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  242. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  243. Wong HS, et al. 2021. Cell. . PubMed
  244. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  245. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  246. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  247. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  248. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  249. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  250. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  251. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  252. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  253. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  254. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  255. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  256. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  257. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  258. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  259. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  260. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  261. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  262. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  263. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  264. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  265. Baasch S, et al. 2021. Cell. . PubMed
  266. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  267. Zheng J, et al. 2020. bioRxiv. . PubMed
  268. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  269. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  270. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  271. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  272. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  273. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  274. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  275. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  276. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  277. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  278. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  279. Welte T, et al. 2021. iScience. 24:103349. PubMed
  280. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  281. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  282. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  283. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  284. Xu S, et al. 2021. Immunity. . PubMed
  285. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  286. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  287. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  288. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  289. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  290. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  291. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  292. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  293. Roy K, et al. 2019. Immunity. 50:616. PubMed
  294. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  295. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  296. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  297. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  298. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  299. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  300. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  301. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  302. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  303. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  304. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  305. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  306. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  307. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  308. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  309. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  310. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  311. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  312. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  313. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  314. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  315. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  316. Zheng J, et al. 2020. Nature. . PubMed
  317. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  318. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  319. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  320. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  321. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  322. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  323. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  324. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  325. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  326. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  327. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  328. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  329. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  330. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  331. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  332. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  333. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  334. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  335. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  336. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  337. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  338. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  339. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  340. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  341. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  342. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  343. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  344. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  345. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  346. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  347. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  348. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  349. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  350. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  351. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  352. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  353. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  354. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  355. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  356. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  357. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  358. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  359. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  360. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  361. Lenert R 2005. J Immunol. 174:2429. PubMed
  362. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  363. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  364. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  365. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  366. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  367. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  368. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  369. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  370. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  371. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  372. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  373. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  374. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  375. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  376. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  377. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  378. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  379. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  380. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  381. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  382. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  383. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  384. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  385. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  386. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  387. Lee SA, et al. 2021. Cells. 10:. PubMed
  388. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  389. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  390. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  391. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  392. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  393. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  394. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  395. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  396. William M, et al. 2018. J Immunol. 200:4102. PubMed
  397. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  398. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  399. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  400. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  401. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  402. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  403. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  404. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  405. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  406. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  407. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  408. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  409. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  410. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  411. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  412. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  413. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  414. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  415. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  416. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  417. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  418. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  419. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  420. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  421. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  422. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  423. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  424. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  425. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  426. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  427. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  428. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  429. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  430. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  431. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  432. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  433. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  434. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  435. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  436. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  437. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  438. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  439. Sibler E, et al. 2021. Cells. 10:. PubMed
  440. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  441. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  442. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  443. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  444. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  445. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  446. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  447. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  448. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  449. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  450. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  451. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  452. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  453. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  454. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  455. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  456. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  457. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  458. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  459. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  460. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  461. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312801 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 01/23/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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