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Spark PLUS UV395™ anti-mouse CD38 Antibody

Pricing & Availability
Clone
S21016F (See other available formats)
Regulatory Status
RUO
Other Names
T10
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
S21016F_SparkPLUSUV395_CD38_Antibody_1_061725-2
C57BL/6 mouse splenocytes were stained with anti-mouse/human CD45R/B220 (clone RA3-6B2) Spark Red™ 718 and anti-mouse CD38 (clone S21016F) Spark PLUS UV395™ (left) or rat IgG2b, κ Spark PLUS UV395™ isotype control (right).
  • S21016F_SparkPLUSUV395_CD38_Antibody_1_061725-2
    C57BL/6 mouse splenocytes were stained with anti-mouse/human CD45R/B220 (clone RA3-6B2) Spark Red™ 718 and anti-mouse CD38 (clone S21016F) Spark PLUS UV395™ (left) or rat IgG2b, κ Spark PLUS UV395™ isotype control (right).
Compare all formats See Spark PLUS UV™ 395 spectral data
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165619 25 µg 140€
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165620 100 µg 308€
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Description

CD38, also known as T10, is a 45 kD type II transmembrane glycoprotein. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is thought to be a ligand of CD38.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse CD38 transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with Spark PLUS UV395™ under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Spark PLUS UV395™ has a maximum excitation of 355 nm and a maximum emission of 385 nm.

Excitation Laser
Ultraviolet Laser (355 nm)
Application Notes

Clone S21016F can completely block the binding of clone “90” on target cells.

Antigen Details

Structure
ADP-ribosyl hydrolase, 42 kD
Distribution

B cells, NK cells, T cell subset, brain, muscle, kidney

Function
Regulation of cellular activation/proliferation, adhesion, metabolism of cADPR and NAADP
Ligand/Receptor
CD31, hyaluronic acid
Cell Type
B cells, Lymphocytes, NK cells, T cells
Biology Area
Cell Biology, Costimulatory Molecules, Immuno-Oncology, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
  2. Shubinsky G, et al. 1997. Immunity. 7:315-24.
  3. Cesano A, et al. 1998. J Immunol. 160:1106-15.
  4. Cockayne DA, et al. 1998. Blood. 92:1324-33.
Gene ID
12494 View all products for this Gene ID
UniProt
View information about CD38 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 06/17/2025

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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