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APC/Cyanine7 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, κ APC/Cyanine7 isotype control (open histogram).
  • 30-F11_APCCyanine7_CD45_Antibody_013019_updated.png
    C57BL/6 splenocytes were stained with CD45 (clone 30-F11) APC/Cyanine7 (filled histogram) or Rat IgG2b, κ APC/Cyanine7 isotype control (open histogram).
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
103115 25 µg 79€
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103116 100 µg 157€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Chang YS, et al. 2020. Int J Mol Sci. 21:00. PubMed
  2. Naito H, et al. 2020. Nature Protocols. 15(3):1066-1081. PubMed
  3. Xing J, et al. 2021. Cell Reports. 35(12):109205. PubMed
  4. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  5. Contijoch EJ et al. 2019. eLife. 8 pii: e40553. PubMed
  6. Wu J et al. 2017. Immunity. 47(6):1114-1128 . PubMed
  7. Komuczki J, et al. 2019. Immunity. 50:1289. PubMed
  8. Wang X, et al. 2019. Cell Res. 29:787. PubMed
  9. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  10. Korsunsky I, et al. 2022. Med. 3:481. PubMed
  11. Cheng C, et al. 2022. Cell Mol Gastroenterol Hepatol. 15:261. PubMed
  12. Pattwell SS, et al. 2022. Sci Adv. 8:eabo6789. PubMed
  13. Schroeter CB, et al. 2022. J Neuroinflammation. 19:270. PubMed
  14. Ho HM, et al. 2022. Pharmaceutics. 14:. PubMed
  15. Cai Z, et al. 2023. Adv Sci (Weinh). 10:e2207155. PubMed
  16. Banerjee K, et al. 2023. Eur J Immunol. 53:e2250161. PubMed
  17. Wu Z, et al. 2023. EMBO Rep. 24:e56524. PubMed
  18. Gao L, et al. 2023. J Nanobiotechnology. 21:56. PubMed
  19. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  20. Lu C, et al. 2023. Antiviral Res. 212:105556. PubMed
  21. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  22. Saha S, et al. 2023. Sci Rep. 13:4609. PubMed
  23. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  24. Freitag PC, et al. 2023. Mol Ther Methods Clin Dev. 29:120. PubMed
  25. Thai LM, et al. 2023. iScience. 26:106477. PubMed
  26. He Q, et al. 2023. Parasit Vectors. 16:139. PubMed
  27. Sasaki L, et al. 2022. Nat Aging. 2:105. PubMed
  28. Haensel D, et al. 2023. Nat Commun. 14:2685. PubMed
  29. Lee K, et al. 2023. JCI Insight. 8:. PubMed
  30. Wang C, et al. 2023. Int J Oral Sci. 15:19. PubMed
  31. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  32. Scieszka DP, et al. 2023. Respir Res. 24:138. PubMed
  33. Yang QC, et al. 2023. iScience. 26:106916. PubMed
  34. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  35. Kato, S., Miyoshi, N., et al. 2025. Ann Surg Oncol. 32(10),7333-7343. PubMed
  36. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  37. Stefkovich M, et al. 2021. Mol Metab. 54:101357. PubMed
  38. Wang Q, et al. 2020. Radiat Environ Biophys. 59:89. PubMed
  39. Kim MY, et al. 2021. JCI Insight. 6:. PubMed
  40. De Vries LCS, et al. 2021. J Crohns Colitis. 15:617. PubMed
  41. Bernasconi R, et al. 2021. EMBO Mol Med. :e14392. PubMed
  42. Miranda K, et al. 2022. iScience. 25:104994. PubMed
  43. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  44. Furrer R, et al. 2021. Sci Adv. 7:eabi4852. PubMed
  45. Ren Y, et al. 2021. Am J Transplant. 21:552. PubMed
  46. Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed
  47. Bruno MEC, et al. 2022. J Cell Physiol. 237:706. PubMed
  48. Cohen K, et al. 2021. Cell Rep. 37:110026. PubMed
  49. Schnell A, et al. 2021. Cell. 184:6281. PubMed
  50. He D, et al. 2022. Immunity. 55:159. PubMed
  51. Alam A, et al. 2022. Cancer Cell. 40:153. PubMed
  52. Goncharov NV, et al. 2022. J Evol Biochem Physiol. 58:230. PubMed
  53. Li DD, et al. 2022. J Cell Mol Med. 26:2438. PubMed
  54. Denorme F, et al. 2022. J Clin Invest. 132: . PubMed
  55. Tang Q, et al. 2022. Mol Ther. 30:2709. PubMed
  56. Chae CS, et al. 2022. Cancer Discov. 12:1904. PubMed
  57. Miyao T, et al. 2022. Elife. 11: . PubMed
  58. Serra M, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:609. PubMed
  59. Poh AR, et al. 2022. Sci Adv. 8:eabl7882. PubMed
  60. Campisi L, et al. 2022. Nature. 606:945. PubMed
  61. Kenigsbuch M, et al. 2022. Nat Neurosci. 25:876. PubMed
  62. Zhao Z, et al. 2022. Adv Sci (Weinh). 9:e2201293. PubMed
  63. Li F, et al. 2022. Gut Microbes. 14:2096989. PubMed
  64. Rodrigues PB, et al. 2022. Cells. 11: . PubMed
  65. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  66. Poh AR, et al. 2022. Cell Rep. 41:111479. PubMed
  67. Zhu X, et al. 2023. Adv Mater. 35:e2207198. PubMed
  68. Li S, et al. 2022. Nat Commun. 13:7371. PubMed
  69. Morrow RJ, et al. 2022. Cells. 11: . PubMed
  70. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  71. Alula KM, et al. 2023. Sci Rep. 13:18. PubMed
  72. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  73. Montilla A, et al. 2023. Cell Death Dis. 14:16. PubMed
  74. Zhou J, et al. 2023. Nutrients. 15: . PubMed
  75. Slusarczyk P, et al. 2023. Elife. 12: . PubMed
  76. Cao Y, et al. 2023. J Inflamm Res. 16:343. PubMed
  77. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  78. Li XF, et al. 2023. J Exp Med. 220: . PubMed
  79. Chun J, et al. 2023. Cancers (Basel). 15: . PubMed
  80. Drummer C, et al. 2023. Front Immunol. 14:1113883. PubMed
  81. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  82. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  83. Marsh SE, et al. 2022. Nat Neurosci. 25:306. PubMed
  84. Gomez-Salinero JM, et al. 2022. Cell Stem Cell. 29:593. PubMed
  85. Hailemichael Y, et al. 2022. Cancer Cell. 40:509. PubMed
  86. Ren D, et al. 2022. STAR Protoc. 3:101217. PubMed
  87. Urban SK, et al. 2020. Liver Int. 40:3103. PubMed
  88. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  89. Rosenkranz SC, et al. 2021. eLife. 10:00. PubMed
  90. Kokona D, et al. 2016. Exp Eye Res. S0014-4835(16)30499-7. PubMed
  91. Page N, et al. 2018. Immunity. 48:937. PubMed
  92. Frisbee AL, et al. 2019. Nat Commun. 10:2712. PubMed
  93. Ajina R, et al. 2019. Oncoimmunology. 8:e1577127. PubMed
  94. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  95. Iwamoto H et al. 2018. Cell metabolism. 28(1):104-117 . PubMed
  96. Lyons J, et al. 2018. PLoS Biol. 16:e2002417. PubMed
  97. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  98. Wu SY, et al. 2022. Mol Cancer. 21:84. PubMed
  99. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  100. Jiang Q, et al. 2022. Theranostics. 12:59. PubMed
  101. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  102. Fan L, et al. 2021. Cancers (Basel). 13:. PubMed
  103. Radovanovic I, et al. 2014. J Immunol. 193:1290. PubMed
  104. Evans H, et al. 2015. J Immunol. 195: 2973 - 2984. PubMed
  105. Cardona S, et al. 2015. ASN Neuro. 7: 1759091415608204. PubMed
  106. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  107. Uzhachenko RV, et al. 2021. Cell Reports. 35(1):108944. PubMed
  108. Ebneter A, et al. 2017. Transl Vis Sci Technol. 10.1167/tvst.6.2.10. PubMed
  109. Kim TJ, et al. 2019. Nat Commun. 10:3258. PubMed
  110. Saleh MM, et al. 2019. Cell Host Microbe. 25:756. PubMed
  111. Blecher-Gonen R, et al. 2019. Cell Syst. 8:109. PubMed
  112. Kashyap AS, et al. 2019. Cell Rep. 28:3367. PubMed
  113. Pluchino N, et al. 2020. J Cell Mol Med. 24:2464. PubMed
  114. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  115. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  116. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 5:64. PubMed
  117. Baram T, et al. 2021. Cells. 10:. PubMed
  118. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  119. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  120. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  121. Adrover JM, et al. 2022. JCI Insight. 7:. PubMed
  122. Steubing RD, et al. 2022. Brain Behav Immun Health. 24:100493. PubMed
  123. Lu H, et al. 2021. Autophagy. 17:2511. PubMed
  124. Kawashima N, et al. 2022. Nat Commun. 13:1624. PubMed
  125. Zhu S, et al. 2022. Front Pharmacol. 13:996635. PubMed
  126. Palacios LM, et al. 2022. Biology (Basel). 11:. PubMed
  127. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  128. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  129. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  130. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  131. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  132. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  133. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  134. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  135. Zhou X, et al. 2022. Front Pharmacol. 13:887263. PubMed
  136. Biswas S, et al. 2021. Nature. 591:464. PubMed
  137. Khandelwal P, et al. 2013. PLoS One. 8:64193. PubMed
  138. Shibata K, et al. 2014. J Immunol. 192:2210. PubMed
  139. Mantia-Smaldone G, et al. 2014. Gynecol Oncol. 133:584. PubMed
  140. Rybalko V, et al. 2015. PLoS One. 10: 0145550. PubMed
  141. AR P, et al. 2016. Circ Res. 118: 400-409. PubMed
  142. Zhu B, et al. 2021. Immunity. 54(6):1200-1218.e9. PubMed
  143. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  144. Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
  145. Uroda T, et al. 2020. Nat Protoc. 15:2107. PubMed
  146. Ganeshan K et al. 2019. Cell. 177(2):399-413 . PubMed
  147. Wiley CD, et al. 2019. JCI Insight. 4:e130056. PubMed
  148. Krasteva G, et al. 2011. Proc Natl Acad Sci U S A. 108:9478. PubMed
  149. Yoon Y, et al. 2021. Cancers (Basel). 13: . PubMed
  150. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  151. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  152. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  153. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
  154. Jung BG, et al. 2022. PLoS Pathog. 18:e1010454. PubMed
  155. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  156. Marangoni F, et al. 2021. Cell. . PubMed
  157. Wang LT, et al. 2021. STAR Protocols. 2(1):100337. PubMed
  158. Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
  159. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  160. Cordeiro O, et al. 2016. PLoS One. 11: 0151848. PubMed
  161. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  162. Huang B, et al. 2020. Cell. 179(5):1160-1176.e24.. PubMed
  163. Ning F, et al. 2019. J Exp Med. 216:1396. PubMed
  164. Higashi AY, et al. 2019. J Am Soc Nephrol. 30:80. PubMed
  165. Lyons J, et al. 2018. Sci Signal. 11. PubMed
  166. Evans R, et al. 2019. Cell Rep. 27:1967. PubMed
  167. Hammond TR, et al. 2019. Immunity. 50:253. PubMed
  168. Schönfeld M, et al. 2021. Alcohol Clin Exp Res. 45:1980. PubMed
  169. Bhattacherjee A, et al. 2021. Mol Neurodegener. 16:19. PubMed
  170. Bagayoko S, et al. 2021. PLoS Pathog. 17:e1009927. PubMed
  171. Liu M, et al. 2020. Cell Rep. 32:107990. PubMed
  172. Jeljeli M, et al. 2020. Cell Rep. 33:108325. PubMed
  173. Montel-Hagen A, et al. 2020. Cell Rep. 33:108320. PubMed
  174. Chi Z, et al. 2020. Molecular Cell. 80(1):43-58.e7. PubMed
  175. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  176. Commerford CD et al. 2018. Cell reports. . PubMed
  177. Zeng J, et al. 2019. Cell Rep. 27:549. PubMed
  178. Yousef H, et al. 2018. Bio Protoc. 8:22. PubMed
  179. Willingham SB, et al. 2018. Cancer Immunol Res. 6:1136. PubMed
  180. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  181. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  182. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  183. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  184. Hillel–Karniel C, et al. 2020. Cell Reports. 30(3):807-819.e4.. PubMed
  185. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  186. Donlan AN, et al. 2020. Anaerobe. 66:102275. PubMed
  187. Uher O, et al. 2021. Cancers (Basel). 13:. PubMed
  188. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  189. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  190. Zhang X, et al. 2020. Elife. 9:00. PubMed
  191. JI B, et al. 2016. Cell Death Differ. 23:759-75. PubMed
  192. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  193. Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed
  194. Bahar Halpern K, et al. 2020. Nat Commun. 11:1936. PubMed
  195. Soldevilla MM, et al. 2019. Mol Ther. 27:1878. PubMed
  196. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  197. Li Y, et al. 2019. Sci Rep. 9:6932. PubMed
  198. Mifflin L, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  199. Stewart JM, et al. 2020. ACS Biomater Sci Eng. 6:5941. PubMed
  200. Gao H, et al. 2021. Cells. 10:. PubMed
  201. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  202. Ajina R, et al. 2021. Cancer Immunol Res. 9:386. PubMed
  203. Veremeyko T, et al. 2012. J Vis Exp. 65: 4097. PubMed
  204. Fu H, et al. 2020. Front Immunol. 11:595813. PubMed
  205. Oladiran O, et al. 2021. J Neuroinflammation. 77:18. PubMed
  206. Ayaub E,et al. 2017. Sci Rep.. 10.1038/s41598-017-13511-z. PubMed
  207. Peralta Ramos JM, et al. 2017. Front Immunol. 1.490277778. PubMed
  208. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  209. Alikhanyan K, et al. 2021. Cancers (Basel). 13:. PubMed
  210. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  211. Ali M, et al. 2022. JCI Insight. 7:. PubMed
  212. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  213. Cho YK, et al. 2022. Nat Commun. 13:4084. PubMed
  214. Ghandhi SA, et al. 2022. Sci Rep. 12:14124. PubMed
  215. Guo P, et al. 2021. J Immunol. 207:408. PubMed
  216. Toubal A, et al. 2020. Nat Commun. 3755:11. PubMed
  217. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  218. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  219. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  220. Martina M, et al. 2014. J Vis Exp. 87: 51192. PubMed
  221. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  222. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  223. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  224. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  225. Neuhöfer P, et al. 2021. Nature. 597:715. PubMed
  226. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  227. Hum NR, et al. 2022. Front Oncol. 12:928474. PubMed
  228. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  229. Selvaraj UM, et al. 2021. Brain Behav Immun. 95:502. PubMed
  230. Ying T, et al. 2021. Am J Physiol Endocrinol Metab. 320:E1148. PubMed
  231. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  232. Momin N, et al. 2022. Nat Commun. 13:109. PubMed
  233. Uddin MJ, et al. 2022. Mucosal Immunol. 15:165. PubMed
  234. Pilones KA, et al. 2020. Cancer Immunol Res. 8:1054. PubMed
  235. Abramowski P, et al. 2014. J Neuroimmunol. 274:111. PubMed
  236. Hoeksema M, et al. 2015. J Immunol. 194:3909. PubMed
  237. Dhanwani R, et al. 2020. Sci Adv. 6:eaba3688. PubMed
  238. Tripathi H, et al. 2020. Stem Cell Rev Rep. 0.953472222. PubMed
  239. Cardenas JJ, et al. 2020. Methods Enzymol. 415:631. PubMed
  240. Alikhanyan K, et al. 2020. Immun Inflamm Dis. 8:181. PubMed
  241. Cheng Y, et al. 2019. Clin Cancer Res. 25:2621. PubMed
  242. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  243. Yang Y, et al. 2022. Elife. 11:. PubMed
  244. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  245. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  246. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  247. Gierut J, et al. 2015. Stem Cell Res. 15: 165-171. PubMed
  248. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  249. Haka A, et al. 2012. PLoS One. 7:e44823. PubMed
  250. Kaya B, et al. 2020. Cell Reports. 32(5):107979. PubMed
  251. Sztwiertnia I, et al. 2020. PLoS One. 15:e0233789. PubMed
  252. Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
  253. Wang R, et al. 2022. Front Immunol. 13:947756. PubMed
  254. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  255. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  256. Maulloo CD, et al. 2021. Front Immunol. 12:714842. PubMed
  257. Clement CC, et al. 2021. Nat Commun. 12:4447. PubMed
  258. Henrich IC, et al. 2021. Cancer Res. 81:2171. PubMed
  259. Huetter J, et al. 2020. Cancer Immunol Res. 0.954861111. PubMed
  260. Favuzzi E, et al. 2021. Cell. 184(15):4048-4063.e32. PubMed
  261. DiToro D, et al. 2020. Immunity. 650:52. PubMed
  262. Veremeyko T, et al. 2019. J Neurosci Res. 97:162. PubMed
  263. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  264. Kim MY, et al. 2018. Cell. 173:1439. PubMed
  265. Camara A, et al. 2019. Immunity. 50:1467. PubMed
  266. Michaelis KA, et al. 2019. Brain Behav Immun. 82:338. PubMed
  267. Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
  268. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  269. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  270. Zhang R, et al. 2022. Front Pharmacol. 13:870848. PubMed
  271. Yu W, et al. 2022. Nat Commun. 13:3544. PubMed
  272. Li D, et al. 2022. Emerg Microbes Infect. 11:2248. PubMed
  273. Ou YC, et al. 2020. ACS Nano. 1.035416667. PubMed
  274. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  275. Zelco A, et al. 2020. Front Cell Neurosci. 0.75625. PubMed
  276. Wang LT, et al. 2020. Cell Rep. 32:108188. PubMed
  277. Hadas R, et al. 2020. JCI Insight. 5:00. PubMed
  278. Stock M, et al. 2015. Osteoarthritis Cartilage. 23: 1221-1225. PubMed
  279. Draper D, et al. 2012. J Immunol. 188:5327. PubMed
  280. Hohsfield LA, et al. 2020. J Neuroinflammation. 0.902083333. PubMed
  281. Godwin MS, et al. 2019. JCI Insight. 4:e126070. PubMed
  282. Yuan X, et al. 2017. Elife. 6:e29540. PubMed
  283. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  284. Selvaraj UM et al. 2018. Endocrinology. 159(11):3848-3859 . PubMed
  285. Pinho–Ribeiro FA, et al. 2018. Cell. 173:1083. PubMed
  286. Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
  287. Hsu M, et al. 2022. Nat Immunol. 23:581. PubMed
  288. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  289. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  290. Wang X, et al. 2022. Front Immunol. 13:864984. PubMed
  291. Galani IE, et al. 2022. STAR Protoc. 3:101151. PubMed
  292. Abdelfattah N, et al. 2022. Nat Commun. 13:767. PubMed
  293. Martina M, et al. 2016. J Am Soc Nephrol. 27: 1113-1123. PubMed
  294. Da Mesquita S, et al. 2021. Science Advances. 7(21):. PubMed
  295. Wakabayashi T et al. 2018. Cell stem cell. 22(3):384-397 . PubMed
  296. Kaiser T, et al. 2019. Eneuro. 6. PubMed
  297. El Agha E, et al. 2017. Cell Stem Cell. 1.014583333. PubMed
  298. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  299. Ben-Moshe S, et al. 2019. Nat Metab. 1:899. PubMed
  300. Bhatt D, et al. 2021. J Exp Med. 218:. PubMed
  301. Lu Z, et al. 2021. J Clin Invest. 131:. PubMed
  302. Luo M, et al. 2021. J Immunol. 207:1683. PubMed
  303. Klein S, et al. 2016. J Cell Sci. 129: 2573 - 2585. PubMed
  304. Yu L, et al. 2020. Nat Commun. 2.045833333. PubMed
  305. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  306. Ji L et al. 2019. Immunity. 51(2):272-284 . PubMed
  307. Jiang P, et al. 2018. Nat Med. 24:1550. PubMed
  308. Wang X, et al. 2018. Nat Commun. 9:551. PubMed
  309. Li N, et al. 2022. Nat Commun. 13:7281. PubMed
  310. Pedicone C, et al. 2022. iScience. 25:104170. PubMed
  311. Godwin MS, et al. 2021. Am J Physiol Lung Cell Mol Physiol. 320:L393. PubMed
  312. Reda M, et al. 2022. Nat Commun. 13:4261. PubMed
  313. Li Y, et al. 2022. STAR Protoc. 3:101364. PubMed
  314. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  315. Milich LM, et al. 2021. J Exp Med. 218:. PubMed
  316. Kline JM, et al. 2021. J Biol Chem. :100373. PubMed
  317. Kiss M, et al. 2020. Cancer Immunol Res. 9:309. PubMed
  318. Starikova E, et al. 2021. Front Pharmacol. 12:667572. PubMed
  319. Yoldi G, et al. 2016. Cancer Res . 76: 5857 - 5869. PubMed
  320. Ling Y, et al. 2016. Pharmacol Res. S1043-6618(16)31329-9. PubMed
  321. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  322. Lu C, et al. 2020. Cancer Cell. 39(1):96-108.e6. PubMed
  323. Yang C, et al. 2020. Cell Host Microbe. 467:27. PubMed
  324. Armaka M, et al. 2018. Nat Commun. 9:618. PubMed
  325. Lang JF et al. 2019. Nat Commun. 10(1):3415 . PubMed
  326. Theurich S et al. 2017. Cell metabolism. 26(1):171-184 . PubMed
  327. Martin A, et al. 2018. Oncotarget. 9:28364. PubMed
  328. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  329. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  330. Ireland L, et al. 2020. Front Immunol. 11:297. PubMed
  331. Gago-Lopez N, et al. 2019. EMBO Mol Med. 11:e10697. PubMed
  332. Van Den Eeckhout B, et al. 2020. NPJ Vaccines. 0.252777778. PubMed
  333. Uluçkan ö, et al. 2020. Cell Reports. 29(4):844-859.e3.. PubMed
  334. Morein D, et al. 2021. Cells. 10: . PubMed
  335. Yan C, et al. 2022. NPJ Precis Oncol. 6:6. PubMed
  336. Phansalkar R, et al. 2021. Elife. 10:. PubMed
  337. Kim S, et al. 2022. Cancers (Basel). 14:. PubMed
  338. Liu SS, et al. 2021. Immunity. :. PubMed
  339. Ukidve A, et al. 2020. Proc Natl Acad Sci U S A. 117:17727. PubMed
  340. E O’Koren, R Mathew, D Saban 2016. Sci Rep. 6:20636. PubMed
  341. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  342. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  343. Seeling M, et al. 2013. Proc Natl Acad Sci U S A. 110:10729. PubMed
  344. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  345. Fransén Pettersson N, et al. 2018. PLoS One. 13:e0203228. PubMed
  346. Winter C, et al. 2018. Cell Metab. 28:175. PubMed
  347. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  348. Peng V, et al. 2022. Nat Immunol. 23:619. PubMed
  349. Wang Y, et al. 2022. Nat Commun. 13:1454. PubMed
  350. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  351. Zhang X, et al. 2022. J Exp Clin Cancer Res. 41:246. PubMed
  352. Guan D, et al. 2021. Cell Death Dis. 12:431. PubMed
  353. Chen YL, et al. 2022. Front Neurosci. 16:876582. PubMed
  354. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  355. Wang J, et al. 2021. Am J Cancer Res. 11:2005. PubMed
  356. Wang X, et al. 2021. Theranostics. 11:209. PubMed
  357. Lux A, et al. 2014. Cell Rep. 10:236. PubMed
  358. Madsen P, et al. 2016. J Neurosci. 36: 5128 - 5143. PubMed
  359. Fox B, et al. 2016. PLoS One. 12: 1006189. PubMed
  360. Parker K, Horn L, Ostrand-Rosenberg S 2016. J Leukoc Biol. 100: 463 - 470.. PubMed
  361. Chen MB, et al. 2020. Cell Rep. 30:4418. PubMed
  362. Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
  363. Wang J, et al. 2020. Cell. 183(7):1867-1883.e26. PubMed
  364. Petriello MC, et al. 2018. Toxicol Sci. 162:548. PubMed
  365. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  366. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  367. Forte E, et al. 2020. Cell Rep. 30:3149. PubMed
  368. Wang J, et al. 2020. J Hematol Oncol. 0.610416667. PubMed
  369. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  370. Cong L, et al. 2021. Breast Cancer Res. 23:51. PubMed
  371. De Micheli AJ, et al. 2020. Am J Physiol Cell Physiol. 319:C885. PubMed
  372. Sibler E, et al. 2021. Cells. 10:. PubMed
  373. Oladiran O, et al. 2021. Front Immunol. 12:720733. PubMed
  374. Schäfer AL, et al. 2021. Front Immunol. 12:696810. PubMed
  375. Sebastian A, et al. 2021. Cells. 10:. PubMed
  376. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  377. Parent AV, et al. 2021. Cell Reports. 36(7):109538. PubMed
  378. Ito Y, et al. 2021. Cell Reports. 35(4):109052. PubMed
  379. Ma Y, et al. 2021. Developmental Cell. 56(4):478-493.e11. PubMed
  380. Ye Y, et al. 2020. Genome Med. 0.557638889. PubMed
  381. Campisi L, et al. 2016. Nat Immunol. 10.1038/ni.3512. PubMed
  382. Holzapfel B, et al. 2015. Biomaterials. 61: 103-114. PubMed
  383. Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
  384. Tong Y, et al. 2018. EBioMedicine. 39:132. PubMed
  385. Lee S, et al. 2021. Autophagy. 18:1062. PubMed
  386. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  387. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  388. Sun D, et al. 2020. PLoS Pathog. 16:e1008361. PubMed
  389. Zhu Q, et al. 2021. J Am Heart Assoc. 10:e023491. PubMed
  390. Amend A, et al. 2021. Int J Mol Sci. 22:. PubMed
RRID
AB_312980 (BioLegend Cat. No. 103115)
AB_312981 (BioLegend Cat. No. 103116)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Spark YG™ 581 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS V475™ anti-mouse CD45 Antibody 30-F11 FC
StarBright UltraViolet 740 anti-mouse CD45 30-F11 FC
PE/Fire™ 744 anti-mouse CD45 30-F11 FC
StarBright UltraViolet 665 anti-mouse CD45 30-F11 FC
Go To Top Version: 3    Revision Date: 01/30/2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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