Loading...

PerCP/Cyanine5.5 anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
30-F11_PerCPCyanine55_CD45_Antibody_082418
C57BL/6 mouse splenocytes were stained with CD45 (Clone 30-F11) PerCP/Cyanine5.5 (filled histogram), or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (open histogram).
  • 30-F11_PerCPCyanine55_CD45_Antibody_082418
    C57BL/6 mouse splenocytes were stained with CD45 (Clone 30-F11) PerCP/Cyanine5.5 (filled histogram), or rat IgG2b, κ PerCP/Cyanine5.5 isotype control (open histogram).
Compare all formats See PerCP/Cyanine5.5 spectral data
Cat # Size Price Quantity Check Availability Save
103131 25 µg 70€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
103132 100 µg 177€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References

(PubMed link indicates BioLegend citation)
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  2. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  3. Pani F, et al. 2021. Endocrinology. 162:. PubMed
  4. Xuan W, et al. 2022. Cancer Immunol Res. 10:770. PubMed
  5. Liu W, et al. 2022. Biomedicines. 10: . PubMed
  6. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  7. Wu X, et al. 2022. J Clin Med. 11: . PubMed
  8. Xie DH, et al. 2022. Med Phys. 49:6728. PubMed
  9. Poh AR, et al. 2022. Cell Rep. 41:111479. PubMed
  10. VanDyke D, et al. 2022. Cell Rep. 41:111478. PubMed
  11. Mansouri S, et al. 2022. J Immunol. 209:2114. PubMed
  12. Lai C, et al. 2023. J Bone Miner Res. 38:86. PubMed
  13. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  14. Xu H, et al. 2022. Aging Dis. 13:1875. PubMed
  15. Zha AH, et al. 2022. Lupus Sci Med. 9: . PubMed
  16. Guo J, et al. 2023. Cell Rep Med. 4:100881. PubMed
  17. Yang L, et al. 2023. Acta Pharmacol Sin. :. PubMed
  18. Liu G, et al. 2023. Commun Biol. 6:102. PubMed
  19. Chan L, et al. 2023. Int J Mol Sci. 24: . PubMed
  20. Kuehm LM, et al. 2021. Cancer Immunol Res. 9:227. PubMed
  21. Khan NZ, et al. 2021. Brain Behav Immun. 92:165. PubMed
  22. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  23. Tang Y, et al. 2022. Dev Cell. 57:480. PubMed
  24. Li X, et al. 2022. Cell. 185:1709. PubMed
  25. Xiong W, et al. 2022. Nat Commun. 13:1700. PubMed
  26. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  27. Jung IY, et al. 2022. Sci Transl Med. 14:eabn7336. PubMed
  28. Choi JG, et al. 2020. Front Immunol. 11:598556. PubMed
  29. Gogoi H, et al. 2020. Front Immunol. 1.620833333. PubMed
  30. Daemen S, et al. 2021. Cell Reports. 34(2):108626. PubMed
  31. Zaman R, et al. 2021. Immunity. :. PubMed
  32. Zhang Q, et al. 2022. Nat Metab. 4:1055. PubMed
  33. Bermea KC, et al. 2022. J Vis Exp. . PubMed
  34. Bajaj R, et al. 2022. Cell Rep. 40:111429. PubMed
  35. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  36. Axelrod ML, et al. 2022. Nature. 611:818. PubMed
  37. Pagni RL, et al. 2022. Front Immunol. 13:1005937. PubMed
  38. Fei F, et al. 2022. Int J Mol Sci. 23:. PubMed
  39. Shi H, et al. 2022. Nutrients. 14:. PubMed
  40. Li J, et al. 2022. Elife. 11:. PubMed
  41. Matsuzawa M, et al. 2023. Nat Commun. 14:1417. PubMed
  42. Xiao Y, et al. 2023. EMBO J. 42:e111762. PubMed
  43. He Y, et al. 2023. Biomolecules. 13:. PubMed
  44. Zhang Z, et al. 2023. Aging Dis. 14:966. PubMed
  45. Doloff JC, et al. 2023. Sci Adv. 9:eade9488. PubMed
  46. Tadic, S., Garc 2025. Int J Mol Sci. 26(21),0. PubMed
  47. Ramakrishna C, et al. 2019. Nat Commun. 10:2153. PubMed
  48. Tan L, et al. 2022. Biochem Biophys Rep. 32:101351. PubMed
  49. Padonou F, et al. 2022. EMBO Rep. 23:e53576. PubMed
  50. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  51. Taddeo A, et al. 2022. NPJ Vaccines. 7:82. PubMed
  52. Li Y, et al. 2022. Int J Biol Sci. 18:3697. PubMed
  53. Tatsuguchi T, et al. 2022. Int Immunol. 34:277. PubMed
  54. Li Z, et al. 2021. Immunology. 163:105. PubMed
  55. Krausgruber T, et al. 2020. Nature. 583:296. PubMed
  56. Kawano H, et al. 2016. Int Immunol. 28: 489 - 501. PubMed
  57. Liu W, et al. 2020. Mol Ther Oncolytics. 17:350. PubMed
  58. Yang H, et al. 2019. Mol Metab. 23:24. PubMed
  59. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  60. Hanhai Z, et al. 2021. Aging (Albany NY). 13:13108. PubMed
  61. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  62. Sasse C, et al. 2022. Pathogens. 11:. PubMed
  63. Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
  64. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  65. Rodda LB et al. 2018. Immunity. 48(5):1014-1028 . PubMed
  66. Barry KC, et al. 2018. Nat Med. 24:1178. PubMed
  67. Hsu SPC, et al. 2020. J Neurooncol. 146:417. PubMed
  68. Yang M, et al. 2020. Cell Prolif. 53:e12784. PubMed
  69. Jazowiecka-Rakus J, et al. 2021. Cancers (Basel). 13:. PubMed
  70. Ren J, et al. 2021. Theranostics. 11:304. PubMed
  71. Craver BM, et al. 2020. Blood Adv. 4:312. PubMed
  72. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  73. Garcia–Agudo LF, et al. 2019. FASEB J. :fj201900337R. PubMed
  74. Zaytseva D, et al. 2018. Physiol Rep. 6:e13812. PubMed
  75. Schmidleithner L et al. 2019. Immunity. 50(5):1232-1248 . PubMed
  76. Biffi G, et al. 2018. Cancer Discov. 2:282. PubMed
  77. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  78. Potluri HK, et al. 2022. J Immunother Cancer. 10:. PubMed
  79. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  80. Liang Z, et al. 2021. J Cell Physiol. 236:4725. PubMed
  81. Fernandez Garcia-Agudo L, et al. 2021. Cell Rep. 36:109548. PubMed
  82. Chung H, et al. 2021. Immune Netw. 21:e28. PubMed
  83. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  84. Peng Z, et al. 2021. STAR Protocols. 2(2):100595. PubMed
  85. Jeong D, et al. 2021. eLife. 0.416666666666667. PubMed
  86. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  87. Damal Villivalam S, et al. 2020. Nat Commun. 4313:11. PubMed
  88. Chaurasiya S, et al. 2020. Oncoimmunology. 9:1729300. PubMed
  89. Somerville TD, et al. 2020. eLife. 9:e53381.. PubMed
  90. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
  91. Sakaguchi M, et al. 2022. Nat Commun. 13:6092. PubMed
  92. Chimenti I, et al. 2022. Cell Death Discov. 8:149. PubMed
  93. Liu Y, et al. 2022. Nat Commun. 13:2665. PubMed
  94. Wang C, et al. 2021. Cell Stem Cell. . PubMed
  95. Fachi JL, et al. 2020. J Exp Med. 217:00:00. PubMed
  96. Voisin M, et al. 2021. Commun Biol. 4:420. PubMed
  97. Edwards CJ, et al. 2021. Br J Cancer. . PubMed
  98. Peres-Emidio EC, et al. 2022. Front Cell Infect Microbiol. 12:811474. PubMed
  99. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  100. Vijay R, et al. 2015. J Exp Med. 212: 1851 - 1868. PubMed
  101. Fleury M, et al. 2015. Development. 142: 3307 - 3320. PubMed
  102. Osborne JK, et al. 2021. Cell Reports. 36(3):109408. PubMed
  103. Wei SC, et al. 2020. Cancer Discov. . PubMed
  104. Vasilijevic J, et al. 2017. PLoS Pathog. 13:e1006650. PubMed
  105. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  106. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  107. Alexander RK, et al. 2020. eLife. 9:e54090.. PubMed
  108. Wang W, et al. 2022. Aging Cell. 21:e13630. PubMed
  109. Lee J, et al. 2022. Nat Commun. 13:1516. PubMed
  110. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  111. Li Z, et al. 2022. J Exp Clin Cancer Res. 41:74. PubMed
  112. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  113. Nicholas DA, et al. 2020. Scientific Reports. 10(1):13063. PubMed
  114. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  115. Linde N, et al. 2018. Nat Commun. 9:21. PubMed
  116. Wu Y, et al. 2021. Nat Commun. 12:2346. PubMed
  117. Shi R, et al. 2022. Theranostics. 12:875. PubMed
  118. Akazawa S, et al. 2021. Diabetologia. 64:878. PubMed
  119. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  120. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  121. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  122. Li N, et al. 2021. eLife. 10:00. PubMed
  123. Zhao J, et al. 2018. Stem Cell Reports. 10:180. PubMed
  124. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  125. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  126. Yang Z, et al. 2021. Sci Adv. 7:. PubMed
  127. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  128. Myerson JW, et al. 2021. Nat Nanotechnol. Online ahead of print. PubMed
  129. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  130. Hu Y, et al. 2021. Bioact Mater. 2905:6. PubMed
  131. Wen Y, et al. 2020. Hypertension. 869:75. PubMed
  132. Hsu CY, et al. 2020. Frontiers in Immunology. 11:574839. PubMed
  133. Bayik D, et al. 2020. Cancer Discov. 1.256944444. PubMed
  134. Horiguchi H, et al. 2019. Genes Dev. 33:1641. PubMed
  135. Adrover JM et al. 2019. Immunity. 50(2):390-402 . PubMed
  136. Christ A, et al. 2018. Cell. 172:162. PubMed
  137. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  138. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  139. Krueger A, et al. 2022. Front Microbiol. 12:789042. PubMed
  140. Mittal A, et al. 2021. Sci Rep. 11:10731. PubMed
  141. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  142. Liu Z, et al. 2015. Development. 142: 2452 - 2463. PubMed
  143. Wang Y, et al. 2020. Cell Death Dis. 1.169444444. PubMed
  144. Sharma M, et al. 2020. Circ Res. 127:335. PubMed
  145. Shao M, et al. 2021. Cell Stem Cell. 28(4):685-701.e7. PubMed
  146. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  147. Du Q et al. 2019. Dev Cell. 49(4):618-631 . PubMed
  148. Branchett WJ, et al. 2020. Wellcome Open Research. 0.278472222. PubMed
  149. Timblin GA, et al. 2021. Nat Metab. 3:618. PubMed
  150. Otvos B, et al. 2021. Clin Cancer Res. 27:2038. PubMed
  151. Lang V, et al. 2021. Elife. 10:. PubMed
  152. Toth K, et al. 2022. PLoS Biol. 20:e3001526. PubMed
  153. Weinstock A, et al. 2021. Elife. :10. PubMed
  154. Joffin N, et al. 2021. Cell Stem Cell. 28(4):702-717.e8. PubMed
  155. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  156. Ballesteros I, et al. 2020. Cell. 183(5):1282-1297.e18. PubMed
  157. Alonso-Herranz L, et al. 2020. Elife. 9:00. PubMed
  158. Sun L, et al. 2015. Sci Rep. 5: 14871. PubMed
  159. Zhang Q, et al. 2021. Front Cell Dev Biol. 9:655552. PubMed
  160. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  161. Thomas K, et al. 2022. JCI Insight. :. PubMed
  162. Xu X, et al. 2022. EMBO Rep. 23:e53509. PubMed
  163. Gomez S, et al. 2022. J Immunother Cancer. 10:. PubMed
  164. Chandra J, et al. 2016. Immunol Cell Biol. 10.1038/icb.2016.83. PubMed
  165. Uematsu T, et al. 2016. Sci Rep. 6:37815. PubMed
  166. Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
  167. Gubin MM, et al. 2018. Cell. 175:1014. PubMed
  168. Li CJ, et al. 2018. J Clin Invest. 128:5251. PubMed
  169. Tao Z, et al. 2019. Clin Cancer Res. 25:1113. PubMed
  170. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  171. Li M, et al. 2021. Cancers (Basel). 13:. PubMed
  172. Dong X, et al. 2022. Front Immunol. 13:896472. PubMed
  173. Pizzurro GA, et al. 2021. Cancers (Basel). 13:. PubMed
  174. Olson B, et al. 2021. Brain Behav Immun. 97:102. PubMed
  175. Calle P, et al. 2021. Cells. 10:. PubMed
  176. Shan B, et al. 2020. Nat Metab. 1332:2. PubMed
  177. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  178. Martomo SA, et al. 2021. Mol Cancer Ther. 1.074305556. PubMed
  179. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  180. Ngamsri KC, et al. 2020. Front Immunol. 11:407. PubMed
  181. Haider N, et al. 2020. Cell Commun Signal. 18:26. PubMed
  182. Bernstock JD, et al. 2019. J Allergy Clin Immunol. 145:358. PubMed
  183. Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed
  184. Karolin A, et al. 2022. Front Pharmacol. 12:789080. PubMed
  185. Jazowiecka-Rakus J, et al. 2020. Mol Ther Oncolytics. 18:335. PubMed
  186. Wong NR, et al. 2021. Immunity. 54:2072. PubMed
  187. Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed
  188. Yu M, et al. 2021. Molecular Cell. 81(6):1216-1230.e9. PubMed
  189. Zhang H, et al. 2021. Cell Reports. 35(6):109096. PubMed
  190. Ko HJ, et al. 2020. Front Immunol. 1897:11. PubMed
  191. Klose A, et al. 2018. JCSM Rapid Commun. 9:20222. PubMed
  192. Casanova-Acebes M, et al. 2018. J Exp Med. 215:2778. PubMed
  193. Chiang N, et al. 2019. J Clin Invest. 129:5294. PubMed
  194. Scott NA, et al. 2018. Front Immunol. 2.319444444. PubMed
  195. Mello AM, et al. 2022. Oncogenesis. 11:56. PubMed
  196. Shaikh H, et al. 2021. Front Immunol. 12:689896. PubMed
  197. Sánchez-del-Campo L, et al. 2021. J Exp Clin Cancer Res. 40:117. PubMed
  198. Steele NG, et al. 2021. Clin Cancer Res. 27:2023. PubMed
  199. Casselli T, et al. 2021. PLoS Pathog. 17:e1009256. PubMed
  200. Mesnieres M, et al. 2021. Cell Reports. 36(8):109618. PubMed
  201. Doss PMIA, et al. 2021. Cell Reports. 34(10):108833. PubMed
  202. Caporarello N, et al. 2020. Aging Cell. 19:e13196. PubMed
  203. Huo M, et al. 2017. FASEB J. 10.1096/fj.201601030R. PubMed
  204. Moufarrij S, et al. 2020. Sci Rep. 10:3470. PubMed
  205. Böhm AM et al. 2019. Dev Cell. 51(2):236-254 . PubMed
  206. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  207. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  208. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  209. Yu H, et al. 2021. Cell Death Dis. 13:1. PubMed
  210. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  211. Zhang Z, et al. 2020. Nature. 579:415. PubMed
  212. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  213. Patel K, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.11. PubMed
  214. Tsunekuni K, et al. 2020. J Clin Med. 9:00. PubMed
  215. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  216. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  217. Chung S, et al. 2020. Am J Physiol Lung Cell Mol Physiol. L921:318. PubMed
  218. Baron CS, et al. 2018. Nat Commun. 9:2517. PubMed
  219. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  220. Miragaia RJ, et al. 2018. Sci Rep. 8:685. PubMed
  221. Rosen SF, et al. 2022. Genome Med. 14:108. PubMed
  222. Schulze J, et al. 2021. Stroke. 52:2939. PubMed
  223. Liu X, et al. 2021. Adv Sci (Weinh). 8:e2100233. PubMed
  224. Liu SS, et al. 2021. Immunity. :. PubMed
  225. Wang Y, et al. 2021. Nat Commun. 0.570833333. PubMed
  226. Gao P, et al. 2020. Front Immunol. 1.636111111. PubMed
  227. Sharma M, et al. 2019. Immunometabolism. 1. PubMed
  228. Liang Z, et al. 2017. Autophagy. 14:505. PubMed
  229. Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed
  230. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  231. Chen Y, et al. 2021. Braz J Med Biol Res. 54:e9570. PubMed
  232. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  233. Deptuch T, et al. 2022. Sci Rep. 12:13480. PubMed
  234. Garcia-Alegria E, et al. 2016. Sci Rep. 6: 25917. PubMed
  235. Kim SI, et al. 2020. Molecular Cancer Therapeutics. 20(1):173-182. PubMed
  236. Durga Devi T, et al. 2017. Am J Pathol. 187:2659. PubMed
  237. Wang L, et al. 2020. Nat Commun. 0.654166667. PubMed
  238. Wirasinha RC, et al. 2021. J Exp Med. 218: . PubMed
  239. Liang Z, et al. 2022. iScience. 25:105233. PubMed
  240. Vogiatzi A, et al. 2021. Mol Cell Biol. 41:e0014921. PubMed
  241. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  242. Li X, et al. 2021. Front Immunol. 12:779560. PubMed
  243. Sheriff L, et al. 2020. Dis Model Mech. 13:dmm046383. PubMed
  244. Zheng QY, et al. 2020. FASEB J. 34:10590. PubMed
  245. Omori S, et al. 2020. Cell Metabolism. 32(5):814-828.e6. PubMed
  246. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  247. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  248. Mitchell LA, et al. 2019. Oncotarget. 10:2252. PubMed
  249. Han Y, et al. 2019. J Clin Invest. 130:26. PubMed
  250. Riopel M, et al. 2019. Mol Metab. 20:89. PubMed
RRID
AB_893344 (BioLegend Cat. No. 103131)
AB_893340 (BioLegend Cat. No. 103132)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

How stable is PerCP/Cyanine5.5 tandem as compared to PerCP alone?

PerCP/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine5 anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine7 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Spark YG™ 581 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS V475™ anti-mouse CD45 Antibody 30-F11 FC
StarBright UltraViolet 740 anti-mouse CD45 30-F11 FC
PE/Fire™ 744 anti-mouse CD45 30-F11 FC
StarBright UltraViolet 665 anti-mouse CD45 30-F11 FC
Go To Top Version: 3    Revision Date: 08/24/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account