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Propidium Iodide Solution Propidium Iodide Solution

Pricing & Availability
Regulatory Status
RUO
Other Names
PI
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421301 2 mL NOK446
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Description

Propidium iodide (PI) is a fluorescent dye that binds to DNA. When excited by 488nm laser light, it can be detected with in the PE/Texas Red® channel with a bandpass filter 610/10. It is commonly used in evaluation of cell viability or DNA content in cell cycle analysis by flow cytometry.

Product Details
Technical Data Sheet (pdf)

Product Details

Formulation
Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/ml
Storage & Handling
The solution should be stored undiluted between 2°C and 8°C, and protect from light. Caution: This solution contains hazardous material; handle with care.
Application

FC - Quality tested
Recommended Usage

The suggested use of this solution for viability staining is 10 µl per million cells in 0.5 ml/test, and incubate for 15 minutes at 4 °C before analysis. For Cell Cycle analysis, please see our Propidium Iodide Cell Cycle Staining Protocol. Caution: This solution is toxigenic and mutagenic; handle with care.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Propidium Iodide Solution can be used in evaluation of apoptosis, cell viability and cell cycle analysis by flow cytometry.

Application References
  1. Vermes I, et al.1995. J. Immunol. Methods 184:39.
  2. Darzynkiewicz Z, et al. 1992. Cytometry 13(8):795.
  3. Douglas RS, et al. 1995. J. Immunol. Methods 188:219.
  4. Sakimoto I, et al. 2006. Cancer Research 66:2287.PubMed
  5. Liu H, et al. 2012. Int J Biochem Cell Biol. 45:408. PubMed
  6. Juel HB, et al. 2013. PLoS One. 8:64619. PubMed
  7. Ren Q, et al. 2013. PLoS One. 8:74732. PubMed
  8. Zhao W, et al. 2013. Clin Immunol. 149:119. PubMed
  9. Beggs KM, et al. 2014. Toxicol Sci. 137:91. PubMed
  10. Ewald SE, et al. 2014. Infect Immun. 82:460. PubMed
  11. Tsou WI, et al. 2014. J Biol Chem. 289:25750. PubMed
  12. Kong S, et al. 2014. J Immunol. 193:5515. PubMed
Product Citations
  1. Liu H, et al. 2012. Int J Biochem Cell Biol. 45:408. PubMed
  2. Ewald S, et al. 2014. Infect Immun . 82:460. PubMed
  3. Guo H, et al. 2016. Sci Rep. 6:37559. PubMed
  4. Smith A, et al. 2017. Sci Rep. 7:41872. PubMed
  5. Li W, et al. 2019. Aging (Albany NY). 0.99375. PubMed
  6. Evans SJ, et al. 2022. Toxicol In Vitro. 83:105415. PubMed
  7. Hagege A, et al. 2022. Cell Rep Med. 3:100659. PubMed
  8. Tintelnot J, et al. 2023. Nature. 615:168. PubMed
  9. Ohuchi K, et al. 2023. Biomed Rep. 18:28. PubMed
  10. Quintela M, et al. 2023. Clin Epigenetics. 15:63. PubMed
  11. Buckley MT, et al. 2023. Nat Aging. 3:121. PubMed
  12. Quintela M, et al. 2023. Br J Cancer. . PubMed
  13. Sohrabi N, et al. 2023. Iran J Public Health. 52:633. PubMed
  14. Papsdorf K, et al. 2023. Nat Cell Biol. 25:672. PubMed
  15. Schwartz PB, et al. 2023. PLoS Genet. 19:e1010770. PubMed
  16. Wyrobnik I, et al. 2023. Oncoimmunology. 12:2219164. PubMed
  17. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  18. Marques de Menezes EG, et al. 2022. MBio. 13:e0300521. PubMed
  19. Das Gupta D, et al. 2022. Cell Death Differ. 29:2163. PubMed
  20. Qin L, et al. 2022. Sci Adv. 8:eabn3774. PubMed
  21. Cheng Y, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:964. PubMed
  22. Choi UY, et al. 2022. Cell Rep. 40:111234. PubMed
  23. Park J, et al. 2022. Animals (Basel). 12: . PubMed
  24. Papakonstantinou A, et al. 2022. Int J Mol Sci. 24: . PubMed
  25. Blal K, et al. 2023. Cancers (Basel). 15: . PubMed
  26. Xiong E, et al. 2023. Front Immunol. 13:1083119. PubMed
  27. Tanaka T, et al. 2023. Nat Immunol. 24:439. PubMed
  28. Bhardwaj M, et al. 2023. J Clin Invest. :. PubMed
  29. Hochrein SM, et al. 2022. Cell Metab. 34:516. PubMed
  30. Wenes M, et al. 2022. Cell Metab. 34:731. PubMed
  31. Chan J, et al. 2017. Oncogene. 10.1038/onc.2017.319. PubMed
  32. Uroda T, et al. 2019. Mol Cell. 75:982. PubMed
  33. Lindqvist B, et al. 2022. PLoS Pathog. 18:e1010555. PubMed
  34. Neumann CKA, et al. 2020. Mol Metab. 34:136. PubMed
  35. Hamel Y, et al. 2021. Cell Rep Med. 2:100370. PubMed
  36. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  37. Leeth C, et al. 2021. Animals (Basel). 11:. PubMed
  38. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  39. McNeal AS, et al. 2021. Elife. 10:. PubMed
  40. Ren Q, et al. 2013. PLoS One. 8:74732. PubMed
  41. He Y, et al. 2020. Nat Commun. 11:1996. PubMed
  42. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  43. Yoshioka H, et al. 2021. Front Cell Dev Biol. 9:621045. PubMed
  44. Yang Y, et al. 2021. Metabolism. 123:154863. PubMed
  45. Sun X, et al. 2022. JCI Insight. 7: . PubMed
  46. Coray M, et al. 2022. Int J Mol Sci. 23:. PubMed
  47. Schrier S, et al. 2016. Sci Rep. 6:34942. PubMed
  48. O'Neill K, et al. 2016. Genes Dev. 30: 973-988. PubMed
  49. Sapanidou V, et al. 2015. Theriogenology. . PubMed
  50. Kong S, et al. 2014. J Immunol. 193:5515. PubMed
  51. Zeng H, et al. 2018. Cancer Cell. 34:56:00. PubMed
  52. Lei W, et al. 2020. Sci Rep. 10:7004. PubMed
  53. Wang Y, et al. 2019. Cell. 179:1144. PubMed
  54. Zhang M, et al. 2017. Oncol Lett. 3.069444444. PubMed
  55. Zhang W, et al. 2021. J Clin Invest. 131:. PubMed
  56. Ambrosi TH, et al. 2021. Elife. 10: . PubMed
  57. Feng L, et al. 2016. J Cell Sci. 129: 2202 - 2212. PubMed
  58. Lange N, et al. 2016. PLoS One. 11: 0160843. PubMed
  59. Jordan PM, et al. 2020. Cell Rep. 33:108247. PubMed
  60. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  61. Liu L, et al. 2019. Cell Prolif. :e12718. PubMed
  62. Zou PA, et al. 2021. Oncol Lett. 22:648. PubMed
  63. Masuda T, et al. 2022. iScience. 25:104781. PubMed
  64. Reighard SD, et al. 2020. Cell Rep Med. :1. PubMed
  65. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  66. Xu B, et al. 2016. Leukemia. 10.1038/leu.2016.297. PubMed
  67. Liu Y, et al. 2017. Acta Biomater. 10.1016/j.actbio.2017.08.021. PubMed
  68. Domenis R, et al. 2017. PLoS One. 10.1371/journal.pone.0169932. PubMed
  69. Walter F, et al. 2020. PLoS One. 15:e0239369. PubMed
  70. Yang M, et al. 2021. Med Sci Monit. 27:e930083. PubMed
  71. Zhang X, et al. 2020. Eur J Med Chem. 112186:192. PubMed
  72. Mensen A, et al. 2015. Biol Blood Marrow Transplant. Available online 10 August 2015. PubMed
  73. Zhao W, et al. 2013. Clin Immunol. 149:119. PubMed
  74. Liu H, et al. 2020. Cell Death Dis. 0.767361111. PubMed
  75. Li L, et al. 2018. Oncol Lett. 4.184722222. PubMed
  76. Jung E, et al. 2017. J Neurosci. 37:6837. PubMed
  77. Basso-Ricci L, et al. 2017. Cytometry A. 10.1002/cyto.a.23148. PubMed
  78. Matsuda K, et al. 2021. Cell Rep Methods. 1:100122. PubMed
  79. Pang K, et al. 2022. Cell Death Dis. 13:169. PubMed
  80. Tang X, et al. 2021. Transl Cancer Res. 10:2120. PubMed
  81. Li Y, et al. 2016. Int J Lower Extrem Wounds. 10.1177/1534734616649485. PubMed
  82. Hu D, et al. 2020. Proc Natl Acad Sci U S A. 117:30639. PubMed
  83. Li Q, et al. 2020. Acta Biochim Biophys Sin (Shanghai). 52:1131. PubMed
  84. Moribe F, et al. 2021. PLoS One. 16:e0237554. PubMed
  85. Litzenburger UM, et al. 2017. Genome Biol. 18:15. PubMed
  86. Shanahan MT, et al. 2021. Am J Physiol Gastrointest Liver Physiol. 321:G668. PubMed
  87. Wang J, et al. 2022. J Clin Invest. :. PubMed
  88. Trudu M, et al. 2022. Front Oncol. 12:968208. PubMed
  89. L Chang, Y Li, D Kaplan 2016. Sci Rep. 6:36862. PubMed
  90. Perl AL, et al. 2019. J Biol Chem. 294:17043. PubMed
  91. Diaz Osterman CJ, et al. 2019. Elife. 8:e47327. PubMed
  92. Hosokawa T, et al. 2017. J Immunol. 10.4049/jimmunol.1700157. PubMed
  93. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0124-1. PubMed
  94. Xue G, et al. 2021. Nat Biomed Eng. 5:1306. PubMed
  95. Lasrado N, et al. 2022. iScience. 25:103865. PubMed
  96. Tsou W, et al. 2014. J Biol Chem. 289:25750. PubMed
  97. Oubaha M, et al. 2016. Sci Transl Med. 8: 362ra144. PubMed
  98. Polk A, et al. 2016. Clin Cancer Res. 22(24):6118-6128. PubMed
  99. Harro CM, et al. 2020. J Clin Invest. . PubMed
  100. Imura Y, et al. 2020. JCI Insight. :5. PubMed
  101. Suzuki S, et al. 2021. STAR Protocols. 2:100683. PubMed
  102. Vickman R, et al. 2016. Mol Cancer Res. 14: 776 - 786. PubMed
  103. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0116-1. PubMed
  104. Xie M, et al. 2017. BMC Cancer . 10.1186/s12885-017-3291-8. PubMed
  105. Pal P, et al. 2021. J Med Chem. 64:14230. PubMed
  106. Hedemann N, et al. 2021. Cancers (Basel). 13:. PubMed
  107. Xie B, et al. 2021. J Immunol. 206:1515. PubMed
  108. M H, et al. 2016. Cell Transplant. 25: 811-27. PubMed
  109. Woo MS, et al. 2021. J Exp Med. :218. PubMed
  110. Huang K, et al. 2018. Biol Open. 7:bio029470. PubMed
  111. Wang H, et al. 2019. Nat Commun. 4.388194444. PubMed
  112. Matsubara T, et al. 2022. J Exp Med. 219:. PubMed
  113. Hughes K, et al. 2017. Open Bio. 10.1098/rsob.160155. PubMed
  114. Resch U, et al. 2016. MBio. 7: e00207-16. PubMed
  115. Bao W, et al. 2016. Sci Rep. 6:22579. PubMed
  116. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  117. Yang X, et al. 2017. J Control Release. 10.1016/j.jconrel.2017.07.014. PubMed
  118. Viereckl MJ, et al. 2022. Biomolecules. 12:. PubMed
  119. Deng Y, et al. 2021. Nat Commun. 12:7041. PubMed
  120. Beggs K, et al. 2014. Toxicol Sci. 137:91. PubMed
  121. Wang C, et al. 2017. Drug Deliv. 10.1080/10717544.2017.1293195. PubMed
  122. Nilsri N, et al. 2021. Sci Rep. 5255:11. PubMed
  123. Bjørnstad R, et al. 2019. Mol Cancer Ther. 1.14375. PubMed
  124. Ghura H, et al. 2021. Neoplasia. 23:837. PubMed
  125. He Y, et al. 2020. J Hematol Oncol. 0.607638889. PubMed
  126. Widodo N, et al. 2022. F1000Res. 11:169. PubMed
  127. Tu Z, et al. 2022. Cell Rep. 40:111072. PubMed
  128. Bensberg M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  129. Namas R, et al. 2016. Lupus Sci Med. 3: e000148. PubMed
  130. Chen Y, et al. 2016. J Biol Chem. 291: 13216 - 13228. PubMed
  131. Deng BB, et al. 2020. Cell Biol Int. 44:1890. PubMed
  132. Siddhartha V, et al. 2017. Artif Cells Nanomed Biotechnol . 10.1080/21691401.2017.1313267. PubMed
  133. Viseshakul N, et al. 2017. Parasitol Res. 10.1007/s00436-017-5589-5. PubMed
  134. Chmielewski M and Abken H 2017. Cell Rep.. 10.1016/j.celrep.2017.11.063. PubMed
  135. Sakimoto I, et al. 2006. Cancer Res. 66:2287. PubMed
  136. Goel S, et al. 2021. Nat Commun. 12:5325. PubMed
  137. Szeto C, et al. 2022. Nat Commun. 13:4951. PubMed
  138. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  139. Mahmoudi M, et al. 2016. Sci Rep. 6:26960. PubMed
  140. Juel H, et al. 2013. PLoS One. 8:64619. PubMed
  141. Popa S, et al. 2020. Wellcome Open Res. 0.249305556. PubMed
  142. Vulin M, et al. 2022. Oncogene. :. PubMed
  143. Liu H, et al. 2012. Int J Biochem Cell Biol. 45:408. PubMed
  144. Ewald S, et al. 2014. Infect Immun . 82:460. PubMed
  145. Guo H, et al. 2016. Sci Rep. 6:37559. PubMed
  146. Smith A, et al. 2017. Sci Rep. 7:41872. PubMed
  147. Li W, et al. 2019. Aging (Albany NY). 0.99375. PubMed
  148. Evans SJ, et al. 2022. Toxicol In Vitro. 83:105415. PubMed
  149. Hagege A, et al. 2022. Cell Rep Med. 3:100659. PubMed
  150. Tintelnot J, et al. 2023. Nature. 615:168. PubMed
  151. Ohuchi K, et al. 2023. Biomed Rep. 18:28. PubMed
  152. Quintela M, et al. 2023. Clin Epigenetics. 15:63. PubMed
  153. Buckley MT, et al. 2023. Nat Aging. 3:121. PubMed
  154. Quintela M, et al. 2023. Br J Cancer. . PubMed
  155. Sohrabi N, et al. 2023. Iran J Public Health. 52:633. PubMed
  156. Papsdorf K, et al. 2023. Nat Cell Biol. 25:672. PubMed
  157. Schwartz PB, et al. 2023. PLoS Genet. 19:e1010770. PubMed
  158. Wyrobnik I, et al. 2023. Oncoimmunology. 12:2219164. PubMed
  159. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  160. Marques de Menezes EG, et al. 2022. MBio. 13:e0300521. PubMed
  161. Das Gupta D, et al. 2022. Cell Death Differ. 29:2163. PubMed
  162. Qin L, et al. 2022. Sci Adv. 8:eabn3774. PubMed
  163. Cheng Y, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:964. PubMed
  164. Choi UY, et al. 2022. Cell Rep. 40:111234. PubMed
  165. Park J, et al. 2022. Animals (Basel). 12: . PubMed
  166. Papakonstantinou A, et al. 2022. Int J Mol Sci. 24: . PubMed
  167. Blal K, et al. 2023. Cancers (Basel). 15: . PubMed
  168. Xiong E, et al. 2023. Front Immunol. 13:1083119. PubMed
  169. Tanaka T, et al. 2023. Nat Immunol. 24:439. PubMed
  170. Bhardwaj M, et al. 2023. J Clin Invest. :. PubMed
  171. Hochrein SM, et al. 2022. Cell Metab. 34:516. PubMed
  172. Wenes M, et al. 2022. Cell Metab. 34:731. PubMed
  173. Chan J, et al. 2017. Oncogene. 10.1038/onc.2017.319. PubMed
  174. Uroda T, et al. 2019. Mol Cell. 75:982. PubMed
  175. Lindqvist B, et al. 2022. PLoS Pathog. 18:e1010555. PubMed
  176. Neumann CKA, et al. 2020. Mol Metab. 34:136. PubMed
  177. Hamel Y, et al. 2021. Cell Rep Med. 2:100370. PubMed
  178. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  179. Leeth C, et al. 2021. Animals (Basel). 11:. PubMed
  180. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  181. McNeal AS, et al. 2021. Elife. 10:. PubMed
  182. Ren Q, et al. 2013. PLoS One. 8:74732. PubMed
  183. He Y, et al. 2020. Nat Commun. 11:1996. PubMed
  184. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  185. Yoshioka H, et al. 2021. Front Cell Dev Biol. 9:621045. PubMed
  186. Yang Y, et al. 2021. Metabolism. 123:154863. PubMed
  187. Sun X, et al. 2022. JCI Insight. 7: . PubMed
  188. Coray M, et al. 2022. Int J Mol Sci. 23:. PubMed
  189. Schrier S, et al. 2016. Sci Rep. 6:34942. PubMed
  190. O'Neill K, et al. 2016. Genes Dev. 30: 973-988. PubMed
  191. Sapanidou V, et al. 2015. Theriogenology. . PubMed
  192. Kong S, et al. 2014. J Immunol. 193:5515. PubMed
  193. Zeng H, et al. 2018. Cancer Cell. 34:56:00. PubMed
  194. Lei W, et al. 2020. Sci Rep. 10:7004. PubMed
  195. Wang Y, et al. 2019. Cell. 179:1144. PubMed
  196. Zhang M, et al. 2017. Oncol Lett. 3.069444444. PubMed
  197. Zhang W, et al. 2021. J Clin Invest. 131:. PubMed
  198. Ambrosi TH, et al. 2021. Elife. 10: . PubMed
  199. Feng L, et al. 2016. J Cell Sci. 129: 2202 - 2212. PubMed
  200. Lange N, et al. 2016. PLoS One. 11: 0160843. PubMed
  201. Jordan PM, et al. 2020. Cell Rep. 33:108247. PubMed
  202. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  203. Liu L, et al. 2019. Cell Prolif. :e12718. PubMed
  204. Zou PA, et al. 2021. Oncol Lett. 22:648. PubMed
  205. Masuda T, et al. 2022. iScience. 25:104781. PubMed
  206. Reighard SD, et al. 2020. Cell Rep Med. :1. PubMed
  207. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  208. Xu B, et al. 2016. Leukemia. 10.1038/leu.2016.297. PubMed
  209. Liu Y, et al. 2017. Acta Biomater. 10.1016/j.actbio.2017.08.021. PubMed
  210. Domenis R, et al. 2017. PLoS One. 10.1371/journal.pone.0169932. PubMed
  211. Walter F, et al. 2020. PLoS One. 15:e0239369. PubMed
  212. Yang M, et al. 2021. Med Sci Monit. 27:e930083. PubMed
  213. Zhang X, et al. 2020. Eur J Med Chem. 112186:192. PubMed
  214. Mensen A, et al. 2015. Biol Blood Marrow Transplant. Available online 10 August 2015. PubMed
  215. Zhao W, et al. 2013. Clin Immunol. 149:119. PubMed
  216. Liu H, et al. 2020. Cell Death Dis. 0.767361111. PubMed
  217. Li L, et al. 2018. Oncol Lett. 4.184722222. PubMed
  218. Jung E, et al. 2017. J Neurosci. 37:6837. PubMed
  219. Basso-Ricci L, et al. 2017. Cytometry A. 10.1002/cyto.a.23148. PubMed
  220. Matsuda K, et al. 2021. Cell Rep Methods. 1:100122. PubMed
  221. Pang K, et al. 2022. Cell Death Dis. 13:169. PubMed
  222. Tang X, et al. 2021. Transl Cancer Res. 10:2120. PubMed
  223. Li Y, et al. 2016. Int J Lower Extrem Wounds. 10.1177/1534734616649485. PubMed
  224. Hu D, et al. 2020. Proc Natl Acad Sci U S A. 117:30639. PubMed
  225. Li Q, et al. 2020. Acta Biochim Biophys Sin (Shanghai). 52:1131. PubMed
  226. Moribe F, et al. 2021. PLoS One. 16:e0237554. PubMed
  227. Litzenburger UM, et al. 2017. Genome Biol. 18:15. PubMed
  228. Shanahan MT, et al. 2021. Am J Physiol Gastrointest Liver Physiol. 321:G668. PubMed
  229. Wang J, et al. 2022. J Clin Invest. :. PubMed
  230. Trudu M, et al. 2022. Front Oncol. 12:968208. PubMed
  231. L Chang, Y Li, D Kaplan 2016. Sci Rep. 6:36862. PubMed
  232. Perl AL, et al. 2019. J Biol Chem. 294:17043. PubMed
  233. Diaz Osterman CJ, et al. 2019. Elife. 8:e47327. PubMed
  234. Hosokawa T, et al. 2017. J Immunol. 10.4049/jimmunol.1700157. PubMed
  235. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0124-1. PubMed
  236. Xue G, et al. 2021. Nat Biomed Eng. 5:1306. PubMed
  237. Lasrado N, et al. 2022. iScience. 25:103865. PubMed
  238. Tsou W, et al. 2014. J Biol Chem. 289:25750. PubMed
  239. Oubaha M, et al. 2016. Sci Transl Med. 8: 362ra144. PubMed
  240. Polk A, et al. 2016. Clin Cancer Res. 22(24):6118-6128. PubMed
  241. Harro CM, et al. 2020. J Clin Invest. . PubMed
  242. Imura Y, et al. 2020. JCI Insight. :5. PubMed
  243. Suzuki S, et al. 2021. STAR Protocols. 2:100683. PubMed
  244. Vickman R, et al. 2016. Mol Cancer Res. 14: 776 - 786. PubMed
  245. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0116-1. PubMed
  246. Xie M, et al. 2017. BMC Cancer . 10.1186/s12885-017-3291-8. PubMed
  247. Pal P, et al. 2021. J Med Chem. 64:14230. PubMed
  248. Hedemann N, et al. 2021. Cancers (Basel). 13:. PubMed
  249. Xie B, et al. 2021. J Immunol. 206:1515. PubMed
  250. M H, et al. 2016. Cell Transplant. 25: 811-27. PubMed
  251. Woo MS, et al. 2021. J Exp Med. :218. PubMed
  252. Huang K, et al. 2018. Biol Open. 7:bio029470. PubMed
  253. Wang H, et al. 2019. Nat Commun. 4.388194444. PubMed
  254. Matsubara T, et al. 2022. J Exp Med. 219:. PubMed
  255. Hughes K, et al. 2017. Open Bio. 10.1098/rsob.160155. PubMed
  256. Resch U, et al. 2016. MBio. 7: e00207-16. PubMed
  257. Bao W, et al. 2016. Sci Rep. 6:22579. PubMed
  258. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  259. Yang X, et al. 2017. J Control Release. 10.1016/j.jconrel.2017.07.014. PubMed
  260. Viereckl MJ, et al. 2022. Biomolecules. 12:. PubMed
  261. Deng Y, et al. 2021. Nat Commun. 12:7041. PubMed
  262. Beggs K, et al. 2014. Toxicol Sci. 137:91. PubMed
  263. Wang C, et al. 2017. Drug Deliv. 10.1080/10717544.2017.1293195. PubMed
  264. Nilsri N, et al. 2021. Sci Rep. 5255:11. PubMed
  265. Bjørnstad R, et al. 2019. Mol Cancer Ther. 1.14375. PubMed
  266. Ghura H, et al. 2021. Neoplasia. 23:837. PubMed
  267. He Y, et al. 2020. J Hematol Oncol. 0.607638889. PubMed
  268. Widodo N, et al. 2022. F1000Res. 11:169. PubMed
  269. Tu Z, et al. 2022. Cell Rep. 40:111072. PubMed
  270. Bensberg M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  271. Namas R, et al. 2016. Lupus Sci Med. 3: e000148. PubMed
  272. Chen Y, et al. 2016. J Biol Chem. 291: 13216 - 13228. PubMed
  273. Deng BB, et al. 2020. Cell Biol Int. 44:1890. PubMed
  274. Siddhartha V, et al. 2017. Artif Cells Nanomed Biotechnol . 10.1080/21691401.2017.1313267. PubMed
  275. Viseshakul N, et al. 2017. Parasitol Res. 10.1007/s00436-017-5589-5. PubMed
  276. Chmielewski M and Abken H 2017. Cell Rep.. 10.1016/j.celrep.2017.11.063. PubMed
  277. Sakimoto I, et al. 2006. Cancer Res. 66:2287. PubMed
  278. Goel S, et al. 2021. Nat Commun. 12:5325. PubMed
  279. Szeto C, et al. 2022. Nat Commun. 13:4951. PubMed
  280. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  281. Mahmoudi M, et al. 2016. Sci Rep. 6:26960. PubMed
  282. Juel H, et al. 2013. PLoS One. 8:64619. PubMed
  283. Popa S, et al. 2020. Wellcome Open Res. 0.249305556. PubMed
  284. Vulin M, et al. 2022. Oncogene. :. PubMed

Antigen Details

Biology Area
Cell Biology, Cell Cycle/DNA Replication, Neuroscience
Gene ID
NA

Related FAQs

Why is washing not recommended after the addition 7-AAD or PI addition when assessing viability?

These dyes bind in equilibrium with DNA. Therefore, external dye concentration must be maintained during analysis and the dye should not be washed out.

Go To Top Version: 2    Revision Date: 10.08.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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Pricing & Availability
Regulatory Status
RUO
Other Names
PI
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421301 2 mL NOK446
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Description

Propidium iodide (PI) is a fluorescent dye that binds to DNA. When excited by 488nm laser light, it can be detected with in the PE/Texas Red® channel with a bandpass filter 610/10. It is commonly used in evaluation of cell viability or DNA content in cell cycle analysis by flow cytometry.

Product Details
Technical Data Sheet (pdf)

Product Details

Formulation
Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/ml
Storage & Handling
The solution should be stored undiluted between 2°C and 8°C, and protect from light. Caution: This solution contains hazardous material; handle with care.
Application

FC - Quality tested
Recommended Usage

The suggested use of this solution for viability staining is 10 µl per million cells in 0.5 ml/test, and incubate for 15 minutes at 4 °C before analysis. For Cell Cycle analysis, please see our Propidium Iodide Cell Cycle Staining Protocol. Caution: This solution is toxigenic and mutagenic; handle with care.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Propidium Iodide Solution can be used in evaluation of apoptosis, cell viability and cell cycle analysis by flow cytometry.

Application References
  1. Vermes I, et al.1995. J. Immunol. Methods 184:39.
  2. Darzynkiewicz Z, et al. 1992. Cytometry 13(8):795.
  3. Douglas RS, et al. 1995. J. Immunol. Methods 188:219.
  4. Sakimoto I, et al. 2006. Cancer Research 66:2287.PubMed
  5. Liu H, et al. 2012. Int J Biochem Cell Biol. 45:408. PubMed
  6. Juel HB, et al. 2013. PLoS One. 8:64619. PubMed
  7. Ren Q, et al. 2013. PLoS One. 8:74732. PubMed
  8. Zhao W, et al. 2013. Clin Immunol. 149:119. PubMed
  9. Beggs KM, et al. 2014. Toxicol Sci. 137:91. PubMed
  10. Ewald SE, et al. 2014. Infect Immun. 82:460. PubMed
  11. Tsou WI, et al. 2014. J Biol Chem. 289:25750. PubMed
  12. Kong S, et al. 2014. J Immunol. 193:5515. PubMed
Product Citations
  1. Liu H, et al. 2012. Int J Biochem Cell Biol. 45:408. PubMed
  2. Ewald S, et al. 2014. Infect Immun . 82:460. PubMed
  3. Guo H, et al. 2016. Sci Rep. 6:37559. PubMed
  4. Smith A, et al. 2017. Sci Rep. 7:41872. PubMed
  5. Li W, et al. 2019. Aging (Albany NY). 0.99375. PubMed
  6. Evans SJ, et al. 2022. Toxicol In Vitro. 83:105415. PubMed
  7. Hagege A, et al. 2022. Cell Rep Med. 3:100659. PubMed
  8. Tintelnot J, et al. 2023. Nature. 615:168. PubMed
  9. Ohuchi K, et al. 2023. Biomed Rep. 18:28. PubMed
  10. Quintela M, et al. 2023. Clin Epigenetics. 15:63. PubMed
  11. Buckley MT, et al. 2023. Nat Aging. 3:121. PubMed
  12. Quintela M, et al. 2023. Br J Cancer. . PubMed
  13. Sohrabi N, et al. 2023. Iran J Public Health. 52:633. PubMed
  14. Papsdorf K, et al. 2023. Nat Cell Biol. 25:672. PubMed
  15. Schwartz PB, et al. 2023. PLoS Genet. 19:e1010770. PubMed
  16. Wyrobnik I, et al. 2023. Oncoimmunology. 12:2219164. PubMed
  17. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  18. Marques de Menezes EG, et al. 2022. MBio. 13:e0300521. PubMed
  19. Das Gupta D, et al. 2022. Cell Death Differ. 29:2163. PubMed
  20. Qin L, et al. 2022. Sci Adv. 8:eabn3774. PubMed
  21. Cheng Y, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:964. PubMed
  22. Choi UY, et al. 2022. Cell Rep. 40:111234. PubMed
  23. Park J, et al. 2022. Animals (Basel). 12: . PubMed
  24. Papakonstantinou A, et al. 2022. Int J Mol Sci. 24: . PubMed
  25. Blal K, et al. 2023. Cancers (Basel). 15: . PubMed
  26. Xiong E, et al. 2023. Front Immunol. 13:1083119. PubMed
  27. Tanaka T, et al. 2023. Nat Immunol. 24:439. PubMed
  28. Bhardwaj M, et al. 2023. J Clin Invest. :. PubMed
  29. Hochrein SM, et al. 2022. Cell Metab. 34:516. PubMed
  30. Wenes M, et al. 2022. Cell Metab. 34:731. PubMed
  31. Chan J, et al. 2017. Oncogene. 10.1038/onc.2017.319. PubMed
  32. Uroda T, et al. 2019. Mol Cell. 75:982. PubMed
  33. Lindqvist B, et al. 2022. PLoS Pathog. 18:e1010555. PubMed
  34. Neumann CKA, et al. 2020. Mol Metab. 34:136. PubMed
  35. Hamel Y, et al. 2021. Cell Rep Med. 2:100370. PubMed
  36. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  37. Leeth C, et al. 2021. Animals (Basel). 11:. PubMed
  38. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  39. McNeal AS, et al. 2021. Elife. 10:. PubMed
  40. Ren Q, et al. 2013. PLoS One. 8:74732. PubMed
  41. He Y, et al. 2020. Nat Commun. 11:1996. PubMed
  42. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  43. Yoshioka H, et al. 2021. Front Cell Dev Biol. 9:621045. PubMed
  44. Yang Y, et al. 2021. Metabolism. 123:154863. PubMed
  45. Sun X, et al. 2022. JCI Insight. 7: . PubMed
  46. Coray M, et al. 2022. Int J Mol Sci. 23:. PubMed
  47. Schrier S, et al. 2016. Sci Rep. 6:34942. PubMed
  48. O'Neill K, et al. 2016. Genes Dev. 30: 973-988. PubMed
  49. Sapanidou V, et al. 2015. Theriogenology. . PubMed
  50. Kong S, et al. 2014. J Immunol. 193:5515. PubMed
  51. Zeng H, et al. 2018. Cancer Cell. 34:56:00. PubMed
  52. Lei W, et al. 2020. Sci Rep. 10:7004. PubMed
  53. Wang Y, et al. 2019. Cell. 179:1144. PubMed
  54. Zhang M, et al. 2017. Oncol Lett. 3.069444444. PubMed
  55. Zhang W, et al. 2021. J Clin Invest. 131:. PubMed
  56. Ambrosi TH, et al. 2021. Elife. 10: . PubMed
  57. Feng L, et al. 2016. J Cell Sci. 129: 2202 - 2212. PubMed
  58. Lange N, et al. 2016. PLoS One. 11: 0160843. PubMed
  59. Jordan PM, et al. 2020. Cell Rep. 33:108247. PubMed
  60. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  61. Liu L, et al. 2019. Cell Prolif. :e12718. PubMed
  62. Zou PA, et al. 2021. Oncol Lett. 22:648. PubMed
  63. Masuda T, et al. 2022. iScience. 25:104781. PubMed
  64. Reighard SD, et al. 2020. Cell Rep Med. :1. PubMed
  65. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  66. Xu B, et al. 2016. Leukemia. 10.1038/leu.2016.297. PubMed
  67. Liu Y, et al. 2017. Acta Biomater. 10.1016/j.actbio.2017.08.021. PubMed
  68. Domenis R, et al. 2017. PLoS One. 10.1371/journal.pone.0169932. PubMed
  69. Walter F, et al. 2020. PLoS One. 15:e0239369. PubMed
  70. Yang M, et al. 2021. Med Sci Monit. 27:e930083. PubMed
  71. Zhang X, et al. 2020. Eur J Med Chem. 112186:192. PubMed
  72. Mensen A, et al. 2015. Biol Blood Marrow Transplant. Available online 10 August 2015. PubMed
  73. Zhao W, et al. 2013. Clin Immunol. 149:119. PubMed
  74. Liu H, et al. 2020. Cell Death Dis. 0.767361111. PubMed
  75. Li L, et al. 2018. Oncol Lett. 4.184722222. PubMed
  76. Jung E, et al. 2017. J Neurosci. 37:6837. PubMed
  77. Basso-Ricci L, et al. 2017. Cytometry A. 10.1002/cyto.a.23148. PubMed
  78. Matsuda K, et al. 2021. Cell Rep Methods. 1:100122. PubMed
  79. Pang K, et al. 2022. Cell Death Dis. 13:169. PubMed
  80. Tang X, et al. 2021. Transl Cancer Res. 10:2120. PubMed
  81. Li Y, et al. 2016. Int J Lower Extrem Wounds. 10.1177/1534734616649485. PubMed
  82. Hu D, et al. 2020. Proc Natl Acad Sci U S A. 117:30639. PubMed
  83. Li Q, et al. 2020. Acta Biochim Biophys Sin (Shanghai). 52:1131. PubMed
  84. Moribe F, et al. 2021. PLoS One. 16:e0237554. PubMed
  85. Litzenburger UM, et al. 2017. Genome Biol. 18:15. PubMed
  86. Shanahan MT, et al. 2021. Am J Physiol Gastrointest Liver Physiol. 321:G668. PubMed
  87. Wang J, et al. 2022. J Clin Invest. :. PubMed
  88. Trudu M, et al. 2022. Front Oncol. 12:968208. PubMed
  89. L Chang, Y Li, D Kaplan 2016. Sci Rep. 6:36862. PubMed
  90. Perl AL, et al. 2019. J Biol Chem. 294:17043. PubMed
  91. Diaz Osterman CJ, et al. 2019. Elife. 8:e47327. PubMed
  92. Hosokawa T, et al. 2017. J Immunol. 10.4049/jimmunol.1700157. PubMed
  93. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0124-1. PubMed
  94. Xue G, et al. 2021. Nat Biomed Eng. 5:1306. PubMed
  95. Lasrado N, et al. 2022. iScience. 25:103865. PubMed
  96. Tsou W, et al. 2014. J Biol Chem. 289:25750. PubMed
  97. Oubaha M, et al. 2016. Sci Transl Med. 8: 362ra144. PubMed
  98. Polk A, et al. 2016. Clin Cancer Res. 22(24):6118-6128. PubMed
  99. Harro CM, et al. 2020. J Clin Invest. . PubMed
  100. Imura Y, et al. 2020. JCI Insight. :5. PubMed
  101. Suzuki S, et al. 2021. STAR Protocols. 2:100683. PubMed
  102. Vickman R, et al. 2016. Mol Cancer Res. 14: 776 - 786. PubMed
  103. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0116-1. PubMed
  104. Xie M, et al. 2017. BMC Cancer . 10.1186/s12885-017-3291-8. PubMed
  105. Pal P, et al. 2021. J Med Chem. 64:14230. PubMed
  106. Hedemann N, et al. 2021. Cancers (Basel). 13:. PubMed
  107. Xie B, et al. 2021. J Immunol. 206:1515. PubMed
  108. M H, et al. 2016. Cell Transplant. 25: 811-27. PubMed
  109. Woo MS, et al. 2021. J Exp Med. :218. PubMed
  110. Huang K, et al. 2018. Biol Open. 7:bio029470. PubMed
  111. Wang H, et al. 2019. Nat Commun. 4.388194444. PubMed
  112. Matsubara T, et al. 2022. J Exp Med. 219:. PubMed
  113. Hughes K, et al. 2017. Open Bio. 10.1098/rsob.160155. PubMed
  114. Resch U, et al. 2016. MBio. 7: e00207-16. PubMed
  115. Bao W, et al. 2016. Sci Rep. 6:22579. PubMed
  116. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  117. Yang X, et al. 2017. J Control Release. 10.1016/j.jconrel.2017.07.014. PubMed
  118. Viereckl MJ, et al. 2022. Biomolecules. 12:. PubMed
  119. Deng Y, et al. 2021. Nat Commun. 12:7041. PubMed
  120. Beggs K, et al. 2014. Toxicol Sci. 137:91. PubMed
  121. Wang C, et al. 2017. Drug Deliv. 10.1080/10717544.2017.1293195. PubMed
  122. Nilsri N, et al. 2021. Sci Rep. 5255:11. PubMed
  123. Bjørnstad R, et al. 2019. Mol Cancer Ther. 1.14375. PubMed
  124. Ghura H, et al. 2021. Neoplasia. 23:837. PubMed
  125. He Y, et al. 2020. J Hematol Oncol. 0.607638889. PubMed
  126. Widodo N, et al. 2022. F1000Res. 11:169. PubMed
  127. Tu Z, et al. 2022. Cell Rep. 40:111072. PubMed
  128. Bensberg M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  129. Namas R, et al. 2016. Lupus Sci Med. 3: e000148. PubMed
  130. Chen Y, et al. 2016. J Biol Chem. 291: 13216 - 13228. PubMed
  131. Deng BB, et al. 2020. Cell Biol Int. 44:1890. PubMed
  132. Siddhartha V, et al. 2017. Artif Cells Nanomed Biotechnol . 10.1080/21691401.2017.1313267. PubMed
  133. Viseshakul N, et al. 2017. Parasitol Res. 10.1007/s00436-017-5589-5. PubMed
  134. Chmielewski M and Abken H 2017. Cell Rep.. 10.1016/j.celrep.2017.11.063. PubMed
  135. Sakimoto I, et al. 2006. Cancer Res. 66:2287. PubMed
  136. Goel S, et al. 2021. Nat Commun. 12:5325. PubMed
  137. Szeto C, et al. 2022. Nat Commun. 13:4951. PubMed
  138. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  139. Mahmoudi M, et al. 2016. Sci Rep. 6:26960. PubMed
  140. Juel H, et al. 2013. PLoS One. 8:64619. PubMed
  141. Popa S, et al. 2020. Wellcome Open Res. 0.249305556. PubMed
  142. Vulin M, et al. 2022. Oncogene. :. PubMed
  143. Liu H, et al. 2012. Int J Biochem Cell Biol. 45:408. PubMed
  144. Ewald S, et al. 2014. Infect Immun . 82:460. PubMed
  145. Guo H, et al. 2016. Sci Rep. 6:37559. PubMed
  146. Smith A, et al. 2017. Sci Rep. 7:41872. PubMed
  147. Li W, et al. 2019. Aging (Albany NY). 0.99375. PubMed
  148. Evans SJ, et al. 2022. Toxicol In Vitro. 83:105415. PubMed
  149. Hagege A, et al. 2022. Cell Rep Med. 3:100659. PubMed
  150. Tintelnot J, et al. 2023. Nature. 615:168. PubMed
  151. Ohuchi K, et al. 2023. Biomed Rep. 18:28. PubMed
  152. Quintela M, et al. 2023. Clin Epigenetics. 15:63. PubMed
  153. Buckley MT, et al. 2023. Nat Aging. 3:121. PubMed
  154. Quintela M, et al. 2023. Br J Cancer. . PubMed
  155. Sohrabi N, et al. 2023. Iran J Public Health. 52:633. PubMed
  156. Papsdorf K, et al. 2023. Nat Cell Biol. 25:672. PubMed
  157. Schwartz PB, et al. 2023. PLoS Genet. 19:e1010770. PubMed
  158. Wyrobnik I, et al. 2023. Oncoimmunology. 12:2219164. PubMed
  159. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  160. Marques de Menezes EG, et al. 2022. MBio. 13:e0300521. PubMed
  161. Das Gupta D, et al. 2022. Cell Death Differ. 29:2163. PubMed
  162. Qin L, et al. 2022. Sci Adv. 8:eabn3774. PubMed
  163. Cheng Y, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:964. PubMed
  164. Choi UY, et al. 2022. Cell Rep. 40:111234. PubMed
  165. Park J, et al. 2022. Animals (Basel). 12: . PubMed
  166. Papakonstantinou A, et al. 2022. Int J Mol Sci. 24: . PubMed
  167. Blal K, et al. 2023. Cancers (Basel). 15: . PubMed
  168. Xiong E, et al. 2023. Front Immunol. 13:1083119. PubMed
  169. Tanaka T, et al. 2023. Nat Immunol. 24:439. PubMed
  170. Bhardwaj M, et al. 2023. J Clin Invest. :. PubMed
  171. Hochrein SM, et al. 2022. Cell Metab. 34:516. PubMed
  172. Wenes M, et al. 2022. Cell Metab. 34:731. PubMed
  173. Chan J, et al. 2017. Oncogene. 10.1038/onc.2017.319. PubMed
  174. Uroda T, et al. 2019. Mol Cell. 75:982. PubMed
  175. Lindqvist B, et al. 2022. PLoS Pathog. 18:e1010555. PubMed
  176. Neumann CKA, et al. 2020. Mol Metab. 34:136. PubMed
  177. Hamel Y, et al. 2021. Cell Rep Med. 2:100370. PubMed
  178. Castellanos CA, et al. 2021. Sci Immunol. 6:eabh0707. PubMed
  179. Leeth C, et al. 2021. Animals (Basel). 11:. PubMed
  180. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  181. McNeal AS, et al. 2021. Elife. 10:. PubMed
  182. Ren Q, et al. 2013. PLoS One. 8:74732. PubMed
  183. He Y, et al. 2020. Nat Commun. 11:1996. PubMed
  184. Fukushima T, et al. 2019. Cell Rep. 29:4144. PubMed
  185. Yoshioka H, et al. 2021. Front Cell Dev Biol. 9:621045. PubMed
  186. Yang Y, et al. 2021. Metabolism. 123:154863. PubMed
  187. Sun X, et al. 2022. JCI Insight. 7: . PubMed
  188. Coray M, et al. 2022. Int J Mol Sci. 23:. PubMed
  189. Schrier S, et al. 2016. Sci Rep. 6:34942. PubMed
  190. O'Neill K, et al. 2016. Genes Dev. 30: 973-988. PubMed
  191. Sapanidou V, et al. 2015. Theriogenology. . PubMed
  192. Kong S, et al. 2014. J Immunol. 193:5515. PubMed
  193. Zeng H, et al. 2018. Cancer Cell. 34:56:00. PubMed
  194. Lei W, et al. 2020. Sci Rep. 10:7004. PubMed
  195. Wang Y, et al. 2019. Cell. 179:1144. PubMed
  196. Zhang M, et al. 2017. Oncol Lett. 3.069444444. PubMed
  197. Zhang W, et al. 2021. J Clin Invest. 131:. PubMed
  198. Ambrosi TH, et al. 2021. Elife. 10: . PubMed
  199. Feng L, et al. 2016. J Cell Sci. 129: 2202 - 2212. PubMed
  200. Lange N, et al. 2016. PLoS One. 11: 0160843. PubMed
  201. Jordan PM, et al. 2020. Cell Rep. 33:108247. PubMed
  202. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  203. Liu L, et al. 2019. Cell Prolif. :e12718. PubMed
  204. Zou PA, et al. 2021. Oncol Lett. 22:648. PubMed
  205. Masuda T, et al. 2022. iScience. 25:104781. PubMed
  206. Reighard SD, et al. 2020. Cell Rep Med. :1. PubMed
  207. Zhang S, et al. 2020. Front Immunol. 1.757638889. PubMed
  208. Xu B, et al. 2016. Leukemia. 10.1038/leu.2016.297. PubMed
  209. Liu Y, et al. 2017. Acta Biomater. 10.1016/j.actbio.2017.08.021. PubMed
  210. Domenis R, et al. 2017. PLoS One. 10.1371/journal.pone.0169932. PubMed
  211. Walter F, et al. 2020. PLoS One. 15:e0239369. PubMed
  212. Yang M, et al. 2021. Med Sci Monit. 27:e930083. PubMed
  213. Zhang X, et al. 2020. Eur J Med Chem. 112186:192. PubMed
  214. Mensen A, et al. 2015. Biol Blood Marrow Transplant. Available online 10 August 2015. PubMed
  215. Zhao W, et al. 2013. Clin Immunol. 149:119. PubMed
  216. Liu H, et al. 2020. Cell Death Dis. 0.767361111. PubMed
  217. Li L, et al. 2018. Oncol Lett. 4.184722222. PubMed
  218. Jung E, et al. 2017. J Neurosci. 37:6837. PubMed
  219. Basso-Ricci L, et al. 2017. Cytometry A. 10.1002/cyto.a.23148. PubMed
  220. Matsuda K, et al. 2021. Cell Rep Methods. 1:100122. PubMed
  221. Pang K, et al. 2022. Cell Death Dis. 13:169. PubMed
  222. Tang X, et al. 2021. Transl Cancer Res. 10:2120. PubMed
  223. Li Y, et al. 2016. Int J Lower Extrem Wounds. 10.1177/1534734616649485. PubMed
  224. Hu D, et al. 2020. Proc Natl Acad Sci U S A. 117:30639. PubMed
  225. Li Q, et al. 2020. Acta Biochim Biophys Sin (Shanghai). 52:1131. PubMed
  226. Moribe F, et al. 2021. PLoS One. 16:e0237554. PubMed
  227. Litzenburger UM, et al. 2017. Genome Biol. 18:15. PubMed
  228. Shanahan MT, et al. 2021. Am J Physiol Gastrointest Liver Physiol. 321:G668. PubMed
  229. Wang J, et al. 2022. J Clin Invest. :. PubMed
  230. Trudu M, et al. 2022. Front Oncol. 12:968208. PubMed
  231. L Chang, Y Li, D Kaplan 2016. Sci Rep. 6:36862. PubMed
  232. Perl AL, et al. 2019. J Biol Chem. 294:17043. PubMed
  233. Diaz Osterman CJ, et al. 2019. Elife. 8:e47327. PubMed
  234. Hosokawa T, et al. 2017. J Immunol. 10.4049/jimmunol.1700157. PubMed
  235. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0124-1. PubMed
  236. Xue G, et al. 2021. Nat Biomed Eng. 5:1306. PubMed
  237. Lasrado N, et al. 2022. iScience. 25:103865. PubMed
  238. Tsou W, et al. 2014. J Biol Chem. 289:25750. PubMed
  239. Oubaha M, et al. 2016. Sci Transl Med. 8: 362ra144. PubMed
  240. Polk A, et al. 2016. Clin Cancer Res. 22(24):6118-6128. PubMed
  241. Harro CM, et al. 2020. J Clin Invest. . PubMed
  242. Imura Y, et al. 2020. JCI Insight. :5. PubMed
  243. Suzuki S, et al. 2021. STAR Protocols. 2:100683. PubMed
  244. Vickman R, et al. 2016. Mol Cancer Res. 14: 776 - 786. PubMed
  245. El-Hafeez A, et al. 2017. Cytotechnology. 10.1007/s10616-017-0116-1. PubMed
  246. Xie M, et al. 2017. BMC Cancer . 10.1186/s12885-017-3291-8. PubMed
  247. Pal P, et al. 2021. J Med Chem. 64:14230. PubMed
  248. Hedemann N, et al. 2021. Cancers (Basel). 13:. PubMed
  249. Xie B, et al. 2021. J Immunol. 206:1515. PubMed
  250. M H, et al. 2016. Cell Transplant. 25: 811-27. PubMed
  251. Woo MS, et al. 2021. J Exp Med. :218. PubMed
  252. Huang K, et al. 2018. Biol Open. 7:bio029470. PubMed
  253. Wang H, et al. 2019. Nat Commun. 4.388194444. PubMed
  254. Matsubara T, et al. 2022. J Exp Med. 219:. PubMed
  255. Hughes K, et al. 2017. Open Bio. 10.1098/rsob.160155. PubMed
  256. Resch U, et al. 2016. MBio. 7: e00207-16. PubMed
  257. Bao W, et al. 2016. Sci Rep. 6:22579. PubMed
  258. Liu X, et al. 2019. Mol Cancer Ther. 18:706. PubMed
  259. Yang X, et al. 2017. J Control Release. 10.1016/j.jconrel.2017.07.014. PubMed
  260. Viereckl MJ, et al. 2022. Biomolecules. 12:. PubMed
  261. Deng Y, et al. 2021. Nat Commun. 12:7041. PubMed
  262. Beggs K, et al. 2014. Toxicol Sci. 137:91. PubMed
  263. Wang C, et al. 2017. Drug Deliv. 10.1080/10717544.2017.1293195. PubMed
  264. Nilsri N, et al. 2021. Sci Rep. 5255:11. PubMed
  265. Bjørnstad R, et al. 2019. Mol Cancer Ther. 1.14375. PubMed
  266. Ghura H, et al. 2021. Neoplasia. 23:837. PubMed
  267. He Y, et al. 2020. J Hematol Oncol. 0.607638889. PubMed
  268. Widodo N, et al. 2022. F1000Res. 11:169. PubMed
  269. Tu Z, et al. 2022. Cell Rep. 40:111072. PubMed
  270. Bensberg M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  271. Namas R, et al. 2016. Lupus Sci Med. 3: e000148. PubMed
  272. Chen Y, et al. 2016. J Biol Chem. 291: 13216 - 13228. PubMed
  273. Deng BB, et al. 2020. Cell Biol Int. 44:1890. PubMed
  274. Siddhartha V, et al. 2017. Artif Cells Nanomed Biotechnol . 10.1080/21691401.2017.1313267. PubMed
  275. Viseshakul N, et al. 2017. Parasitol Res. 10.1007/s00436-017-5589-5. PubMed
  276. Chmielewski M and Abken H 2017. Cell Rep.. 10.1016/j.celrep.2017.11.063. PubMed
  277. Sakimoto I, et al. 2006. Cancer Res. 66:2287. PubMed
  278. Goel S, et al. 2021. Nat Commun. 12:5325. PubMed
  279. Szeto C, et al. 2022. Nat Commun. 13:4951. PubMed
  280. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  281. Mahmoudi M, et al. 2016. Sci Rep. 6:26960. PubMed
  282. Juel H, et al. 2013. PLoS One. 8:64619. PubMed
  283. Popa S, et al. 2020. Wellcome Open Res. 0.249305556. PubMed
  284. Vulin M, et al. 2022. Oncogene. :. PubMed

Antigen Details

Biology Area
Cell Biology, Cell Cycle/DNA Replication, Neuroscience
Gene ID
NA

Related FAQs

Why is washing not recommended after the addition 7-AAD or PI addition when assessing viability?

These dyes bind in equilibrium with DNA. Therefore, external dye concentration must be maintained during analysis and the dye should not be washed out.

Go To Top Version: 2    Revision Date: 10.08.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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